Injectable biodegradable hybrid hydrogels based on thiolated collagen and oligo(acryloyl carbonate)–poly(ethylene glycol)–oligo(acryloyl carbonate) copolymer for functional cardiac regeneration

[Display omitted] Injectable biodegradable hybrid hydrogels were designed and developed based on thiolated collagen (Col-SH) and multiple acrylate containing oligo(acryloyl carbonate)-b-poly(ethylene glycol)-b-oligo(acryloyl carbonate) (OAC-PEG-OAC) copolymers for functional cardiac regeneration. Hy...

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Veröffentlicht in:	Acta biomaterialia 2015-03, Vol.15, p.55-64
Hauptverfasser:	Xu, Guohui, Wang, Xiaolin, Deng, Chao, Teng, Xiaomei, Suuronen, Erik J., Shen, Zhenya, Zhong, Zhiyuan
Format:	Artikel
Sprache:	eng
Schlagworte:	Acrylates - pharmacology Animals Biocompatible Materials - pharmacology Biodegradability Blood Vessels - drug effects Blood Vessels - pathology Carbonates Cell Adhesion - drug effects Cell Proliferation - drug effects Collagen Collagen - chemical synthesis Collagen - chemistry Collagen - pharmacology Collagens Copolymers Degradation Elastic Modulus - drug effects Female Heart - physiopathology Heart Function Tests Hybrid hydrogels Hydrogels Hydrogels - chemical synthesis Hydrogels - chemistry Hydrogels - pharmacology Injectable hydrogels Injections Mathematical models Myocardial infarction Myocardial Infarction - diagnostic imaging Myocardial Infarction - pathology Myocardial Infarction - physiopathology Polyethylene Glycols - pharmacology Rats, Sprague-Dawley Regeneration Regeneration - drug effects Rheology - drug effects Stem cells Sulfhydryl Compounds - chemical synthesis Sulfhydryl Compounds - chemistry Sulfhydryl Compounds - pharmacology Sus scrofa Ultrasonography
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