Pollutants bioavailability and toxicological risk from microplastics to marine mussels
Microplastics represent a growing environmental concern for the oceans due to their potential of adsorbing chemical pollutants, thus representing a still unexplored source of exposure for aquatic organisms. In this study polyethylene (PE) and polystyrene (PS) microplastics were shown to adsorb pyren...
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Veröffentlicht in: | Environmental pollution (1987) 2015-03, Vol.198, p.211-222 |
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creator | Avio, Carlo Giacomo Gorbi, Stefania Milan, Massimo Benedetti, Maura Fattorini, Daniele d'Errico, Giuseppe Pauletto, Marianna Bargelloni, Luca Regoli, Francesco |
description | Microplastics represent a growing environmental concern for the oceans due to their potential of adsorbing chemical pollutants, thus representing a still unexplored source of exposure for aquatic organisms. In this study polyethylene (PE) and polystyrene (PS) microplastics were shown to adsorb pyrene with a time and dose-dependent relationship. Results also indicated a marked capability of contaminated microplastics to transfer this model PAH to exposed mussels Mytilus galloprovincialis; tissue localization of microplastics occurred in haemolymph, gills and especially digestive tissues where a marked accumulation of pyrene was also observed. Cellular effects included alterations of immunological responses, lysosomal compartment, peroxisomal proliferation, antioxidant system, neurotoxic effects, onset of genotoxicity; changes in gene expression profile was also demonstrated through a new DNA microarray platform. The study provided the evidence that microplastics adsorb PAHs, emphasizing an elevated bioavailability of these chemicals after the ingestion, and the toxicological implications due to responsiveness of several molecular and cellular pathways to microplastics.
•Polyethylene and polystyrene microplastics efficiently adsorbed pyrene.•Pyrene adsorbed on microplastics was readily bioavailable for mussels.•Microplastics affected several molecular and cellular pathways.•Potential toxicological risk can arise from virgin and contaminated microplastics.
Pyrene adsorbed on microplastics is accumulated in tissues of marine mussels. Transcriptional and cellular responses highlight the potential risk of virgin and contaminated polymers. |
doi_str_mv | 10.1016/j.envpol.2014.12.021 |
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•Polyethylene and polystyrene microplastics efficiently adsorbed pyrene.•Pyrene adsorbed on microplastics was readily bioavailable for mussels.•Microplastics affected several molecular and cellular pathways.•Potential toxicological risk can arise from virgin and contaminated microplastics.
Pyrene adsorbed on microplastics is accumulated in tissues of marine mussels. Transcriptional and cellular responses highlight the potential risk of virgin and contaminated polymers.</description><identifier>ISSN: 0269-7491</identifier><identifier>EISSN: 1873-6424</identifier><identifier>DOI: 10.1016/j.envpol.2014.12.021</identifier><identifier>PMID: 25637744</identifier><language>eng</language><publisher>England: Elsevier Ltd</publisher><subject>Animals ; Aquatic Organisms ; Bioavailability ; Biomarkers ; Bivalvia - metabolism ; Cellular ; DNA Damage ; Exposure ; Gills - metabolism ; Hazardous Substances - metabolism ; Microplastic ; Mussels ; Mytilus - metabolism ; Mytilus galloprovincialis ; Oceans and Seas ; PAHs ; Plastics - metabolism ; Plastics - toxicity ; Pollutants ; Polyallylamine hydrochloride ; Polycyclic Aromatic Hydrocarbons - metabolism ; Polyethylenes ; Polystyrene resins ; Pyrenes ; Risk Assessment ; Transcriptomics ; Water Pollutants, Chemical - metabolism ; Water Pollutants, Chemical - toxicity</subject><ispartof>Environmental pollution (1987), 2015-03, Vol.198, p.211-222</ispartof><rights>2014 Elsevier Ltd</rights><rights>Copyright © 2014 Elsevier Ltd. All rights reserved.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c540t-e746c3f46d840ca251a53d9c12b3784f0833ab8fa76eb63be0d6883731b5df493</citedby><cites>FETCH-LOGICAL-c540t-e746c3f46d840ca251a53d9c12b3784f0833ab8fa76eb63be0d6883731b5df493</cites><orcidid>0000-0003-1667-8038 ; 0000-0001-6084-6188 ; 0000-0002-5847-4722 ; 0000-0002-3067-7421</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.envpol.2014.12.021$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25637744$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Avio, Carlo Giacomo</creatorcontrib><creatorcontrib>Gorbi, Stefania</creatorcontrib><creatorcontrib>Milan, Massimo</creatorcontrib><creatorcontrib>Benedetti, Maura</creatorcontrib><creatorcontrib>Fattorini, Daniele</creatorcontrib><creatorcontrib>d'Errico, Giuseppe</creatorcontrib><creatorcontrib>Pauletto, Marianna</creatorcontrib><creatorcontrib>Bargelloni, Luca</creatorcontrib><creatorcontrib>Regoli, Francesco</creatorcontrib><title>Pollutants bioavailability and toxicological risk from microplastics to marine mussels</title><title>Environmental pollution (1987)</title><addtitle>Environ Pollut</addtitle><description>Microplastics represent a growing environmental concern for the oceans due to their potential of adsorbing chemical pollutants, thus representing a still unexplored source of exposure for aquatic organisms. In this study polyethylene (PE) and polystyrene (PS) microplastics were shown to adsorb pyrene with a time and dose-dependent relationship. Results also indicated a marked capability of contaminated microplastics to transfer this model PAH to exposed mussels Mytilus galloprovincialis; tissue localization of microplastics occurred in haemolymph, gills and especially digestive tissues where a marked accumulation of pyrene was also observed. Cellular effects included alterations of immunological responses, lysosomal compartment, peroxisomal proliferation, antioxidant system, neurotoxic effects, onset of genotoxicity; changes in gene expression profile was also demonstrated through a new DNA microarray platform. The study provided the evidence that microplastics adsorb PAHs, emphasizing an elevated bioavailability of these chemicals after the ingestion, and the toxicological implications due to responsiveness of several molecular and cellular pathways to microplastics.
•Polyethylene and polystyrene microplastics efficiently adsorbed pyrene.•Pyrene adsorbed on microplastics was readily bioavailable for mussels.•Microplastics affected several molecular and cellular pathways.•Potential toxicological risk can arise from virgin and contaminated microplastics.
Pyrene adsorbed on microplastics is accumulated in tissues of marine mussels. Transcriptional and cellular responses highlight the potential risk of virgin and contaminated polymers.</description><subject>Animals</subject><subject>Aquatic Organisms</subject><subject>Bioavailability</subject><subject>Biomarkers</subject><subject>Bivalvia - metabolism</subject><subject>Cellular</subject><subject>DNA Damage</subject><subject>Exposure</subject><subject>Gills - metabolism</subject><subject>Hazardous Substances - metabolism</subject><subject>Microplastic</subject><subject>Mussels</subject><subject>Mytilus - metabolism</subject><subject>Mytilus galloprovincialis</subject><subject>Oceans and Seas</subject><subject>PAHs</subject><subject>Plastics - metabolism</subject><subject>Plastics - toxicity</subject><subject>Pollutants</subject><subject>Polyallylamine hydrochloride</subject><subject>Polycyclic Aromatic Hydrocarbons - metabolism</subject><subject>Polyethylenes</subject><subject>Polystyrene resins</subject><subject>Pyrenes</subject><subject>Risk Assessment</subject><subject>Transcriptomics</subject><subject>Water Pollutants, Chemical - metabolism</subject><subject>Water Pollutants, Chemical - toxicity</subject><issn>0269-7491</issn><issn>1873-6424</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkEtLxDAUhYMozjj6D0S6dNOaV5N0I4j4AkEX6jak6a1kTJsxaQf993YYdSmu7ua753A-hI4JLggm4mxZQL9eBV9QTHhBaIEp2UFzoiTLBad8F80xFVUueUVm6CClJcaYM8b20YyWgknJ-Ry9PAbvx8H0Q8pqF8zaOG9q593wmZm-yYbw4Wzw4dVZ47Po0lvWxtBlnbMxrLxJg7NporLORNdD1o0pgU-HaK81PsHR912g5-urp8vb_P7h5u7y4j63JcdDDpILy1ouGsWxNbQkpmRNZQmtmVS8xYoxU6vWSAG1YDXgRijFJCN12bS8Ygt0us1dxfA-Qhp055IF700PYUyaCCmrSlWS_AdlTFV4yl8gvkWnjSlFaPUqumngpyZYb-Trpd7K1xv5mlA9yZ_eTr4bxrqD5vfpx_YEnG-ByRCsHUSdrIPeQuMi2EE3wf3d8AV3tJir</recordid><startdate>20150301</startdate><enddate>20150301</enddate><creator>Avio, Carlo Giacomo</creator><creator>Gorbi, Stefania</creator><creator>Milan, Massimo</creator><creator>Benedetti, Maura</creator><creator>Fattorini, Daniele</creator><creator>d'Errico, Giuseppe</creator><creator>Pauletto, Marianna</creator><creator>Bargelloni, Luca</creator><creator>Regoli, Francesco</creator><general>Elsevier Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7ST</scope><scope>7TN</scope><scope>7TV</scope><scope>7U1</scope><scope>7U2</scope><scope>7U7</scope><scope>C1K</scope><scope>F1W</scope><scope>H95</scope><scope>L.G</scope><scope>SOI</scope><scope>7SU</scope><scope>8FD</scope><scope>FR3</scope><scope>KR7</scope><orcidid>https://orcid.org/0000-0003-1667-8038</orcidid><orcidid>https://orcid.org/0000-0001-6084-6188</orcidid><orcidid>https://orcid.org/0000-0002-5847-4722</orcidid><orcidid>https://orcid.org/0000-0002-3067-7421</orcidid></search><sort><creationdate>20150301</creationdate><title>Pollutants bioavailability and toxicological risk from microplastics to marine mussels</title><author>Avio, Carlo Giacomo ; 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In this study polyethylene (PE) and polystyrene (PS) microplastics were shown to adsorb pyrene with a time and dose-dependent relationship. Results also indicated a marked capability of contaminated microplastics to transfer this model PAH to exposed mussels Mytilus galloprovincialis; tissue localization of microplastics occurred in haemolymph, gills and especially digestive tissues where a marked accumulation of pyrene was also observed. Cellular effects included alterations of immunological responses, lysosomal compartment, peroxisomal proliferation, antioxidant system, neurotoxic effects, onset of genotoxicity; changes in gene expression profile was also demonstrated through a new DNA microarray platform. The study provided the evidence that microplastics adsorb PAHs, emphasizing an elevated bioavailability of these chemicals after the ingestion, and the toxicological implications due to responsiveness of several molecular and cellular pathways to microplastics.
•Polyethylene and polystyrene microplastics efficiently adsorbed pyrene.•Pyrene adsorbed on microplastics was readily bioavailable for mussels.•Microplastics affected several molecular and cellular pathways.•Potential toxicological risk can arise from virgin and contaminated microplastics.
Pyrene adsorbed on microplastics is accumulated in tissues of marine mussels. Transcriptional and cellular responses highlight the potential risk of virgin and contaminated polymers.</abstract><cop>England</cop><pub>Elsevier Ltd</pub><pmid>25637744</pmid><doi>10.1016/j.envpol.2014.12.021</doi><tpages>12</tpages><orcidid>https://orcid.org/0000-0003-1667-8038</orcidid><orcidid>https://orcid.org/0000-0001-6084-6188</orcidid><orcidid>https://orcid.org/0000-0002-5847-4722</orcidid><orcidid>https://orcid.org/0000-0002-3067-7421</orcidid><oa>free_for_read</oa></addata></record> |
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subjects | Animals Aquatic Organisms Bioavailability Biomarkers Bivalvia - metabolism Cellular DNA Damage Exposure Gills - metabolism Hazardous Substances - metabolism Microplastic Mussels Mytilus - metabolism Mytilus galloprovincialis Oceans and Seas PAHs Plastics - metabolism Plastics - toxicity Pollutants Polyallylamine hydrochloride Polycyclic Aromatic Hydrocarbons - metabolism Polyethylenes Polystyrene resins Pyrenes Risk Assessment Transcriptomics Water Pollutants, Chemical - metabolism Water Pollutants, Chemical - toxicity |
title | Pollutants bioavailability and toxicological risk from microplastics to marine mussels |
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