Mitochondrion-Targeted Photosensitizer Enhances the Photodynamic Effect-Induced Mitochondrial Dysfunction and Apoptosis

: Recently, the mitochondrion has been considered as a novel pharmacological target for anticancer therapy due to its crucial role involved in arbitrating cell apoptosis. We have previously demonstrated that 488‐nm laser irradiation induced a specific mitochondrial reactive oxygen species (mROS) for...

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Veröffentlicht in:Annals of the New York Academy of Sciences 2005-05, Vol.1042 (1), p.419-428
Hauptverfasser: PENG, TSUNG-I, CHANG, CHENG-JEN, GUO, MEI-JIN, WANG, YU-HUAI, YU, JAU-SONG, WU, HONG-YUEH, JOU, MEI-JIE
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Sprache:eng
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