Enhanced Stem Cell Pluripotency in Surface-Modified Electrospun Fibrous Matrices

A previously screened “hit chemistry” (N‐[3‐(dimethylamino)propyl] methacrylamide) that supports strong attachment and long‐term self‐renewal of ES cells is selected and grafted to poly(ether sulfone) (PES) fibrous matrices through plasma‐induced graft polymerization. The 3D modified fibers exhibit...

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Veröffentlicht in:	Macromolecular bioscience 2014-02, Vol.14 (2), p.215-224
Hauptverfasser:	Zonca Jr, Michael R., Yune, Philip S., Williams, James K., Gu, Minghao, Unser, Andrea M., Imbrogno, Joseph, Belfort, Georges, Xie, Yubing
Format:	Artikel
Sprache:	eng
Schlagworte:	Acrylamides - chemistry Animals Attachment Biomarkers - metabolism Cell Culture Techniques - methods Cell Differentiation Cell growth Cell Proliferation Chemistry Techniques, Synthetic dimethylaminopropyl methacrylamide Electrospinning Embryos Grafting Markers Mice Microscopy, Electrochemical, Scanning modification nanofibers Nanofibers - ultrastructure Photoelectron Spectroscopy Pluripotent Stem Cells - cytology Pluripotent Stem Cells - metabolism poly(ether sulfones) Stem cells Sulfones - chemistry Surface chemistry Surface Properties Synthesis Three dimensional Two dimensional
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