Cell shape-dependent shear stress on adherent cells in a micro-physiologic system as revealed by FEM

Flow-induced shear stress on adherent cells leads to biochemical signaling and mechanical responses of the cells. To determine the flow-induced shear stress on adherent cells cultured in a micro-scaled reaction chamber, we developed a suitable finite element method model. The influence of the most i...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Physiological measurement 2015-05, Vol.36 (5), p.955-966
Hauptverfasser:	Pfister, C, Bozsak, C, Wolf, P, Demmel, F, Brischwein, M
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Adhesion Cell Line Cell Shape extracellular acidification rate fibroblast Finite Element Analysis finite element method Hydrodynamics Mice oxygen uptake rate Reproducibility of Results Shear Strength shear stress Stress, Mechanical
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!