Functions of inflammatory factor in non-tumor deep venous thrombosis of lower extremity
To explore the functions of inflammatory cytokine, tissue factor (TF) and cancer procoagulant (CP) in non-tumor deep venous thrombosis (NT-DVT). A total of 17 NT-DVT patients (5 males and 12 females) were selected for NT-DVT group while 20 voluntary (10 males and 10 females) blood donors for control...
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| Veröffentlicht in: | Zhong hua yi xue za zhi 2015-03, Vol.95 (8), p.598-600 |
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| container_title | Zhong hua yi xue za zhi |
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| creator | Sun, Xing Shen, Lianjun Gu, Wei Shan, Dan Ren, Minmin Qiu, Hua Gu, Jian |
| description | To explore the functions of inflammatory cytokine, tissue factor (TF) and cancer procoagulant (CP) in non-tumor deep venous thrombosis (NT-DVT).
A total of 17 NT-DVT patients (5 males and 12 females) were selected for NT-DVT group while 20 voluntary (10 males and 10 females) blood donors for control group from May 2012 to March 2013. The levels of inflammatory cytokines interleukin 1β (IL-1 β), IL-18, tumor necrosis factor alpha (TNF-α), TF and CP were tested by enzyme-linked immunosorbent assay (ELISA) before and after treatment. Also the correlations of inflammatory cytokines and TF were determined.
The levels of inflammatory cytokines and TF were higher in NT-DVT than those in control group pre-treatment ((153.13 ± 2.30) vs (59.26 ± 1.57) ng/L, (364.27 ± 1.46) vs (67.46 ± 1.48) ng/L, (363.51 ± 1.85) vs (216.42 ± 1.55) µg/L, (66.90 ± 1.44) vs (14.55 ± 1.52) ng/L, all P < 0.05). And after anticoagulant therapy, the levels decreased (all P < 0.05). Also the levels of IL-1β,IL-18 and TNF-α were positively corr |
| doi_str_mv | 10.3760/cma.j.issn.0376-2491.2015.08.009 |
| format | Article |
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A total of 17 NT-DVT patients (5 males and 12 females) were selected for NT-DVT group while 20 voluntary (10 males and 10 females) blood donors for control group from May 2012 to March 2013. The levels of inflammatory cytokines interleukin 1β (IL-1 β), IL-18, tumor necrosis factor alpha (TNF-α), TF and CP were tested by enzyme-linked immunosorbent assay (ELISA) before and after treatment. Also the correlations of inflammatory cytokines and TF were determined.
The levels of inflammatory cytokines and TF were higher in NT-DVT than those in control group pre-treatment ((153.13 ± 2.30) vs (59.26 ± 1.57) ng/L, (364.27 ± 1.46) vs (67.46 ± 1.48) ng/L, (363.51 ± 1.85) vs (216.42 ± 1.55) µg/L, (66.90 ± 1.44) vs (14.55 ± 1.52) ng/L, all P < 0.05). And after anticoagulant therapy, the levels decreased (all P < 0.05). Also the levels of IL-1β,IL-18 and TNF-α were positively corr</description><identifier>ISSN: 0376-2491</identifier><identifier>DOI: 10.3760/cma.j.issn.0376-2491.2015.08.009</identifier><identifier>PMID: 25917036</identifier><language>chi</language><publisher>China</publisher><subject>Cytokines ; Enzyme-Linked Immunosorbent Assay ; Female ; Humans ; Inflammation ; Leg ; Lower Extremity ; Male ; Neoplasms ; Thromboplastin ; Venous Thrombosis</subject><ispartof>Zhong hua yi xue za zhi, 2015-03, Vol.95 (8), p.598-600</ispartof><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27903,27904</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25917036$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Sun, Xing</creatorcontrib><creatorcontrib>Shen, Lianjun</creatorcontrib><creatorcontrib>Gu, Wei</creatorcontrib><creatorcontrib>Shan, Dan</creatorcontrib><creatorcontrib>Ren, Minmin</creatorcontrib><creatorcontrib>Qiu, Hua</creatorcontrib><creatorcontrib>Gu, Jian</creatorcontrib><title>Functions of inflammatory factor in non-tumor deep venous thrombosis of lower extremity</title><title>Zhong hua yi xue za zhi</title><addtitle>Zhonghua Yi Xue Za Zhi</addtitle><description>To explore the functions of inflammatory cytokine, tissue factor (TF) and cancer procoagulant (CP) in non-tumor deep venous thrombosis (NT-DVT).
A total of 17 NT-DVT patients (5 males and 12 females) were selected for NT-DVT group while 20 voluntary (10 males and 10 females) blood donors for control group from May 2012 to March 2013. The levels of inflammatory cytokines interleukin 1β (IL-1 β), IL-18, tumor necrosis factor alpha (TNF-α), TF and CP were tested by enzyme-linked immunosorbent assay (ELISA) before and after treatment. Also the correlations of inflammatory cytokines and TF were determined.
The levels of inflammatory cytokines and TF were higher in NT-DVT than those in control group pre-treatment ((153.13 ± 2.30) vs (59.26 ± 1.57) ng/L, (364.27 ± 1.46) vs (67.46 ± 1.48) ng/L, (363.51 ± 1.85) vs (216.42 ± 1.55) µg/L, (66.90 ± 1.44) vs (14.55 ± 1.52) ng/L, all P < 0.05). And after anticoagulant therapy, the levels decreased (all P < 0.05). Also the levels of IL-1β,IL-18 and TNF-α were positively corr</description><subject>Cytokines</subject><subject>Enzyme-Linked Immunosorbent Assay</subject><subject>Female</subject><subject>Humans</subject><subject>Inflammation</subject><subject>Leg</subject><subject>Lower Extremity</subject><subject>Male</subject><subject>Neoplasms</subject><subject>Thromboplastin</subject><subject>Venous Thrombosis</subject><issn>0376-2491</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kE9LxDAUxHNQ3GXdryA97qU1f5qkOcriqrDgRfFY0vQVI01Sm1Ttt7fo6mmYHzOPxyC0I7hgUuBr43TxVtgYfYEXkNNSkYJiwgtcFRirM7T-5yu0jdE2uJRMUUzJBVpRrojETKzRy2HyJtngYxa6zPqu187pFMY567RZdGGZDz5Pk1tMCzBkH-DDFLP0OgbXhGh_qn34hDGDrzSCs2m-ROed7iNsT7pBz4fbp_19fny8e9jfHPOBKJFyUEISWnGjKWs7WgFuBKOGCqVwVXKtqhITVmKpOi6oYAAtk0zikjbcGNBsg3a_d4cxvE8QU-1sNND32sPyZE2ElFXFueBL9OoUnRoHbT2M1ulxrv_GYN8xqWT0</recordid><startdate>20150303</startdate><enddate>20150303</enddate><creator>Sun, Xing</creator><creator>Shen, Lianjun</creator><creator>Gu, Wei</creator><creator>Shan, Dan</creator><creator>Ren, Minmin</creator><creator>Qiu, Hua</creator><creator>Gu, Jian</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>20150303</creationdate><title>Functions of inflammatory factor in non-tumor deep venous thrombosis of lower extremity</title><author>Sun, Xing ; Shen, Lianjun ; Gu, Wei ; Shan, Dan ; Ren, Minmin ; Qiu, Hua ; Gu, Jian</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p196t-e9671285ca23df28e0b632c26990845a9840134079f56263eed3737042b5ccea3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>chi</language><creationdate>2015</creationdate><topic>Cytokines</topic><topic>Enzyme-Linked Immunosorbent Assay</topic><topic>Female</topic><topic>Humans</topic><topic>Inflammation</topic><topic>Leg</topic><topic>Lower Extremity</topic><topic>Male</topic><topic>Neoplasms</topic><topic>Thromboplastin</topic><topic>Venous Thrombosis</topic><toplevel>online_resources</toplevel><creatorcontrib>Sun, Xing</creatorcontrib><creatorcontrib>Shen, Lianjun</creatorcontrib><creatorcontrib>Gu, Wei</creatorcontrib><creatorcontrib>Shan, Dan</creatorcontrib><creatorcontrib>Ren, Minmin</creatorcontrib><creatorcontrib>Qiu, Hua</creatorcontrib><creatorcontrib>Gu, Jian</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Zhong hua yi xue za zhi</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Sun, Xing</au><au>Shen, Lianjun</au><au>Gu, Wei</au><au>Shan, Dan</au><au>Ren, Minmin</au><au>Qiu, Hua</au><au>Gu, Jian</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Functions of inflammatory factor in non-tumor deep venous thrombosis of lower extremity</atitle><jtitle>Zhong hua yi xue za zhi</jtitle><addtitle>Zhonghua Yi Xue Za Zhi</addtitle><date>2015-03-03</date><risdate>2015</risdate><volume>95</volume><issue>8</issue><spage>598</spage><epage>600</epage><pages>598-600</pages><issn>0376-2491</issn><abstract>To explore the functions of inflammatory cytokine, tissue factor (TF) and cancer procoagulant (CP) in non-tumor deep venous thrombosis (NT-DVT).
A total of 17 NT-DVT patients (5 males and 12 females) were selected for NT-DVT group while 20 voluntary (10 males and 10 females) blood donors for control group from May 2012 to March 2013. The levels of inflammatory cytokines interleukin 1β (IL-1 β), IL-18, tumor necrosis factor alpha (TNF-α), TF and CP were tested by enzyme-linked immunosorbent assay (ELISA) before and after treatment. Also the correlations of inflammatory cytokines and TF were determined.
The levels of inflammatory cytokines and TF were higher in NT-DVT than those in control group pre-treatment ((153.13 ± 2.30) vs (59.26 ± 1.57) ng/L, (364.27 ± 1.46) vs (67.46 ± 1.48) ng/L, (363.51 ± 1.85) vs (216.42 ± 1.55) µg/L, (66.90 ± 1.44) vs (14.55 ± 1.52) ng/L, all P < 0.05). And after anticoagulant therapy, the levels decreased (all P < 0.05). Also the levels of IL-1β,IL-18 and TNF-α were positively corr</abstract><cop>China</cop><pmid>25917036</pmid><doi>10.3760/cma.j.issn.0376-2491.2015.08.009</doi><tpages>3</tpages></addata></record> |
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| ispartof | Zhong hua yi xue za zhi, 2015-03, Vol.95 (8), p.598-600 |
| issn | 0376-2491 |
| language | chi |
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| source | MEDLINE; EZB-FREE-00999 freely available EZB journals |
| subjects | Cytokines Enzyme-Linked Immunosorbent Assay Female Humans Inflammation Leg Lower Extremity Male Neoplasms Thromboplastin Venous Thrombosis |
| title | Functions of inflammatory factor in non-tumor deep venous thrombosis of lower extremity |
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