Targeted Deletion of the Murine Lgr4 Gene Decreases Lens Epithelial Cell Resistance to Oxidative Stress and Induces Age-Related Cataract Formation: e0119599

Oxidative stress contributes to the formation of cataracts. The leucine rich repeat containing G protein-coupled receptor 4 (LGR4, also known as GPR48), is important in many developmental processes. Since deletion of Lgr4 has previously been shown to lead to cataract formation in mice, we sought to...

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Veröffentlicht in:	PloS one 2015-03, Vol.10 (3)
Hauptverfasser:	Zhu, Jun, Hou, Qiang, Dong, Xiang Da, Wang, Zhenlian, Chen, Xiaoyan, Zheng, Dandan, Zhou, Linglin, He, Chao, Liu, Mingyao, Tu, LiLi
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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