Germacrone inhibits early stages of influenza virus infection

•Germacrone is a major component of the essential oil extracted from Rhizoma Curcuma.•Germacrone has antiviral effect against several influenza viruses dose-dependently.•The early stages of the viral life cycle are affected by germacrone.•Germacrone showed an effective protection of mice from lethal...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Antiviral research 2013-12, Vol.100 (3), p.578-588
Hauptverfasser:	Liao, Qingjiao, Qian, Zhengxu, Liu, Rui, An, Liwei, Chen, Xulin
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibiotics. Antiinfectious agents. Antiparasitic agents Antiviral agents Antiviral Agents - administration & dosage Antiviral Agents - pharmacology Antiviral Agents - therapeutic use Biological and medical sciences Cell Line Chick Embryo Curcuma Dogs Dose-Response Relationship, Drug Drug Evaluation, Preclinical Drug Therapy, Combination Drugs, Chinese Herbal - administration & dosage Drugs, Chinese Herbal - pharmacology Drugs, Chinese Herbal - therapeutic use Germacrone Humans Infectious diseases Influenza A Virus, H1N1 Subtype - drug effects Influenza A Virus, H1N1 Subtype - physiology Influenza A Virus, H3N2 Subtype - drug effects Influenza A Virus, H3N2 Subtype - physiology Influenza B virus Influenza B virus - drug effects Influenza B virus - physiology Influenza virus Inhibitor Lung - virology Madin Darby Canine Kidney Cells Medical sciences Mice Orthomyxoviridae Infections - drug therapy Orthomyxoviridae Infections - prevention & control Oseltamivir - administration & dosage Oseltamivir - pharmacology Oseltamivir - therapeutic use Pharmacology. Drug treatments Phytotherapy Ribavirin - pharmacology Sesquiterpenes, Germacrane - administration & dosage Sesquiterpenes, Germacrane - pharmacology Sesquiterpenes, Germacrane - therapeutic use Specific Pathogen-Free Organisms Viral diseases Virus Attachment - drug effects Virus Cultivation Virus Replication - drug effects
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!