Complement — tapping into new sites and effector systems

Recent studies have shown that complement activation is not confined to the serum but also occurs within cellular compartments. This has led to an emerging understanding that complement components can intersect diverse cellular metabolic and effector pathways. Here, the authors propose that the diff...

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Veröffentlicht in:	Nature reviews. Immunology 2014-12, Vol.14 (12), p.811-820
Hauptverfasser:	Kolev, Martin, Friec, Gaelle Le, Kemper, Claudia
Format:	Artikel
Sprache:	eng
Schlagworte:	631/250/2501 631/250/262 Adaptive immunity Animals Antigens B-Lymphocytes - immunology Biomedicine Complement (Immunology) Complement Activation - immunology Complement System Proteins - immunology Enzymes Growth factors Humans Immune response Immunity, Innate - immunology Immunology Inflammasomes - immunology Metabolism Mice Microorganisms opinion-2 Pathogens Physiology Properties Proteins Receptors, Complement - immunology Receptors, Growth Factor - immunology Receptors, Notch - immunology T-Lymphocytes - immunology
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