Genome Wide DNA Methylation Profiles Provide Clues to the Origin and Pathogenesis of Germ Cell Tumors: e0122146

The cell of origin of the five subtypes (I-V) of germ cell tumors (GCTs) are assumed to be germ cells from different maturation stages. This is (potentially) reflected in their methylation status as fetal maturing primordial germ cells are globally demethylated during migration from the yolk sac to...

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Veröffentlicht in:PloS one 2015-04, Vol.10 (4)
Hauptverfasser: Rijlaarsdam, Martin A, Tax, David MJ, Gillis, Ad JM, Dorssers, Lambert CJ, Koestler, Devin C, Ridder, Jeroen de, Looijenga, Leendert HJ
Format: Artikel
Sprache:eng
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