Composites of peptide nucleic acids with titanium dioxide nanoparticles. IV. Antiviral activity of nanocomposites containing DNA/PNA duplexes

Antiviral activity of TiO 2 · PL · DNA/PNA nanobiocomposites was studied on the MDCK cell culture infected with influenza A virus (H3N2 subtype). A PNA fragment in nanocomposites was electrostatically bound in the form of a DNA/PNA heteroduplex to titanium dioxide nanoparticles precovered with polyl...

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Veröffentlicht in:	Bioorganicheskaia khimiia 2015-03, Vol.41 (2), p.140-146
Hauptverfasser:	Amirkhanov, R. N., Mazurkova, N. A., Amirkhanov, N. V., Zarytova, V. F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antiviral Agents - chemistry Antiviral Agents - pharmacology Biochemistry Biomedical and Life Sciences Biomedicine Bioorganic Chemistry DNA - chemistry DNA - pharmacology Dogs Influenza A virus Influenza A virus - metabolism Life Sciences Madin Darby Canine Kidney Cells Nanocomposites - chemistry Organic Chemistry Orthomyxoviridae Infections - drug therapy Orthomyxoviridae Infections - metabolism Peptide Nucleic Acids - chemistry Peptide Nucleic Acids - pharmacology Titanium - chemistry Titanium - pharmacology
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