Anti-inflammatory properties of fruit juices enriched with pine bark extract in an in vitro model of inflamed human intestinal epithelium: The effect of gastrointestinal digestion

► Anti-inflammatory effect of fruit juices enriched with pine bark extract. ► IL-8, nitric oxide, TEER and ROS production by Caco-2 cells were used as inflammatory markers. ► In vitro gastrointestinal digestion process reduces the anti-inflammatory properties of enriched fruit juices. Enrichment of...

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Veröffentlicht in:	Food and chemical toxicology 2013-03, Vol.53, p.94-99
Hauptverfasser:	Frontela-Saseta, Carmen, López-Nicolás, Rubén, González-Bermúdez, Carlos A., Martínez-Graciá, Carmen, Ros-Berruezo, Gaspar
Format:	Artikel
Sprache:	eng
Schlagworte:	Ananas - chemistry Animals anti-inflammatory activity Anti-Inflammatory Agents - pharmacology bark Beverages - analysis bioavailability Biological and medical sciences Caco-2 Cells coculture digestion Digestion - drug effects Fruit - chemistry Fruit juices Gut inflammation human cell lines Humans In vitro digestion inflammation Inflammation - drug therapy interleukin-8 Interleukin-8 - analysis Interleukin-8 - metabolism intestinal mucosa Intestinal Mucosa - drug effects Intestinal Mucosa - metabolism macrophages Male Medical sciences Mice nitric oxide Nitric Oxide - analysis Nitric Oxide - metabolism phenolic compounds Pine bark extract pineapples Pinus - chemistry Plant Bark - chemistry Plant Extracts - pharmacology reactive oxygen species Reactive Oxygen Species - metabolism Toxicology
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