Parenteral pentazocine and diabetes mellitus: a double whammy for cutaneous complication

Parenteral pentazocine and diabetes mellitus: a double whammy for cutaneous complication

Pentazocine, a non-narcotic analgesic, though has no addictive potential but abused frequently via parenteral route for its psychological dependence. It causes local sclerosis resulting in non-healing ulcer at injection sites. Diabetes mellitus suppress host immunity, making them vulnerable to vario...

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Veröffentlicht in:Journal of the Association of Physicians of India 2014-10, Vol.62 (10), p.52-54
Hauptverfasser: Phaujdar, Sibaji, Sarkar, Rathindra Nath, Bhattacharyya, Kuntal
Format: Artikel
Sprache:eng
Schlagworte:
Diabetes Mellitus, Type 2 - complications
Drug Eruptions - etiology
Humans
Male
Middle Aged
Narcotics - adverse effects
Pentazocine - adverse effects
Substance Abuse, Intravenous - complications
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container_title Journal of the Association of Physicians of India
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creator Phaujdar, Sibaji
Sarkar, Rathindra Nath
Bhattacharyya, Kuntal
description Pentazocine, a non-narcotic analgesic, though has no addictive potential but abused frequently via parenteral route for its psychological dependence. It causes local sclerosis resulting in non-healing ulcer at injection sites. Diabetes mellitus suppress host immunity, making them vulnerable to various bacterial skin and soft tissue infection among which mkethicillin resistant staphylococcus aureus (MRSA) infection are predominant. We report a case, a 50-year-old shopkeeper who used to inject pentazocine primarily as analgesic, later became addicted to it. Blindly injecting the drug in any approachable soft tissue resulted in woody induration of local skin with multiple ulcers in his both arms. He later developed type 2 Diabetes mellitus which made the scenario even worser.
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source MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Alma/SFX Local Collection
subjects Diabetes Mellitus, Type 2 - complications
Drug Eruptions - etiology
Humans
Male
Middle Aged
Narcotics - adverse effects
Pentazocine - adverse effects
Substance Abuse, Intravenous - complications
title Parenteral pentazocine and diabetes mellitus: a double whammy for cutaneous complication
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