Phenotypic analysis of spleen, thymus, and peripheral blood cells in aged C57Bl/6 mice following long-term exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin

A mouse model was used to identify potential biomarkers of exposure to the environmental contaminant 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Female C57B1/6 mice were treated weekly with 0.2 mu g TCDD/kg body weight or vehicle for 14-15 months. Phenotypic analysis by flow cytometry identified the...

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Veröffentlicht in:	Fundamental and applied toxicology 1995, Vol.25 (1), p.60-69
Hauptverfasser:	OUGHTON, J. A, PEREIRA, C. B, DEKREY, G. K, COLLIER, J. M, FRANK, A. A, KERKVLIET, N. I
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Chemical and industrial products toxicology. Toxic occupational diseases Medical sciences Toxicology Various organic compounds
Online-Zugang:	Volltext
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