Comparing PMMA and calcium sulfate as carriers for the local delivery of antibiotics to infected surgical sites

Antibiotic-loaded bone cement is a primary option for treatment of orthopedic infections. Poly(methyl methacrylate) (PMMA) is a widely used cement that, when loaded with antibiotics in spacer or bead form, has been shown to reduce infection rates. However, PMMA is not resorbable and requires a secon...

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Veröffentlicht in:Journal of biomedical materials research. Part B, Applied biomaterials Applied biomaterials, 2015-05, Vol.103 (4), p.870-877
Hauptverfasser: McConoughey, Stephen J., Howlin, Robert P., Wiseman, Jessica, Stoodley, Paul, Calhoun, Jason H.
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Sprache:eng
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