Centrosome-Associated Degradation Limits β-Catenin Inheritance by Daughter Cells after Asymmetric Division

Caenorhabditis elegans embryos rapidly diversify cell fate using a modified Wnt/β-catenin signaling strategy to carry out serial asymmetric cell divisions (ACDs). Wnt-dependent ACDs rely on nuclear asymmetry of the transcriptional coactivator SYS-1/β-catenin between daughter cells to differentially...

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Veröffentlicht in:	Current biology 2015-04, Vol.25 (8), p.1005-1016
Hauptverfasser:	Vora, Setu, Phillips, Bryan T.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Asymmetric Cell Division - genetics Asymmetric Cell Division - physiology beta Catenin - metabolism Caenorhabditis elegans - cytology Caenorhabditis elegans Proteins - metabolism Centrosome - metabolism Proteasome Endopeptidase Complex - metabolism Proteolysis Signal Transduction - genetics Transcription Factors - metabolism Wnt Proteins - metabolism
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