Smac Therapeutic Peptide Nanoparticles Inducing Apoptosis of Cancer Cells for Combination Chemotherapy with Doxorubicin

Smac-conjugated nanoparticle (Smac-NP) was designed to induce the apoptosis of cancer cells and as a drug carrier for combination therapy. It contained three parts, a SmacN7 peptide which could induce apoptosis of cancer cells by interacting with XIAPs, the cell penetrating domain rich in arginine,...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	ACS applied materials & interfaces 2015-04, Vol.7 (15), p.8005-8012
Hauptverfasser:	Li, Mingxing, Liu, Peng, Gao, Guanhui, Deng, Jizhe, Pan, Zhengyin, Wu, Xu, Xie, Gaofeng, Yue, Caixia, Cho, Chi Hin, Ma, Yifan, Cai, Lintao
Format:	Artikel
Sprache:	eng
Schlagworte:	Antimetabolites, Antineoplastic - administration & dosage Antimetabolites, Antineoplastic - chemistry Antineoplastic Combined Chemotherapy Protocols - administration & dosage Antineoplastic Combined Chemotherapy Protocols - chemistry Apoptosis - drug effects Cell Line, Tumor Diffusion Doxorubicin - administration & dosage Humans Nanocapsules - administration & dosage Nanocapsules - chemistry Nanocapsules - ultrastructure Neoplasms, Experimental - drug therapy Neoplasms, Experimental - pathology Oligopeptides - administration & dosage
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!