Idarubicin, High-dose Cytarabine and Etoposide for Remission Induction in Therapy-Related Acute Myeloid Leukemia

Five patients with therapy-related acute myeloid leukemia received combination induction chemotherapy with idarubicin, high-dose cytarabine, and etoposide. Complete remission was achieved in all patients with a single course of therapy. Treatment-related toxicity included nausea, vomiting, mucositis...

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Veröffentlicht in:	Leukemia & lymphoma 1994, Vol.15 (1-2), p.127-130
Hauptverfasser:	Philpott, Nicola, Mehta, Jayesh, Treleaven, Jennie, Powles, Ray
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Disease Adult Anemia, Refractory, with Excess of Blasts - chemically induced Anemia, Refractory, with Excess of Blasts - drug therapy Antineoplastic Combined Chemotherapy Protocols - adverse effects Antineoplastic Combined Chemotherapy Protocols - therapeutic use Blood Transfusion Bone Marrow Diseases - chemically induced Bone Marrow Diseases - therapy Bone Marrow Transplantation Combined Modality Therapy Cytarabine - administration & dosage Cytarabine - adverse effects Etoposide - administration & dosage Etoposide - adverse effects Female Gastrointestinal Diseases - chemically induced Humans Idarubicin - administration & dosage Idarubicin - adverse effects Leukemia, Myeloid - chemically induced Leukemia, Myeloid - drug therapy Leukemia, Myeloid - therapy Leukemia, Radiation-Induced - drug therapy Leukemia, Radiation-Induced - therapy Male Middle Aged Neoplasms - drug therapy Neoplasms - radiotherapy Prospective Studies Radiotherapy - adverse effects Remission Induction Salvage Therapy Treatment Outcome
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