Changes in the permeability of the blood-brain barrier in acute hyperammonemia : effect of dexamethasone

This study was designed to determine the contribution of elevated plasma ammonia levels to blood-brain barrier (BBB) abnormalities in the presence of intact liver. The permeability changes of the BBB were investigated grossly with Evans blue (EB) and quantitatively by measuring the blood-to-brain tr...

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Veröffentlicht in:	Molecular and chemical neuropathology 1993-12, Vol.20 (3), p.203-218
Hauptverfasser:	ZIYLAN, Y. Z, ÜZÜM, G, BERNARD, G, DILER, A. S, BOURRE, J.-M
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetates - pharmacokinetics Aminoisobutyric Acids - pharmacokinetics Ammonia - blood Ammonia - metabolism Animals Behavior, Animal - drug effects Biological and medical sciences Blood Volume - physiology Blood-Brain Barrier - drug effects Brain Chemistry - drug effects Capillary Permeability - drug effects Coma - chemically induced Dexamethasone - pharmacology Electroencephalography - drug effects Endothelium, Vascular - drug effects Endothelium, Vascular - metabolism Evans Blue Hormones. Endocrine system Male Medical sciences Pharmacology. Drug treatments Rats Rats, Sprague-Dawley
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