Design, synthesis, in vitro antiproliferative evaluation, and kinase inhibitory effects of a new series of imidazo[2,1-b]thiazole derivatives

Design and synthesis of a new series of 5,6-diarylimidazo[2,1-b]thiazole derivatives possessing terminal aryl sulfonamide moiety are described. Their in vitro antiproliferative activities against a panel of 57 human cancer cell lines of nine different cancer types were tested at the NCI. Compounds 8...

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Veröffentlicht in:European journal of medicinal chemistry 2015-05, Vol.95, p.453-463
Hauptverfasser: Abdel-Maksoud, Mohammed S., Kim, Mi-Ryeong, El-Gamal, Mohammed I., Gamal El-Din, Mahmoud M., Tae, Jinsung, Choi, Hong Seok, Lee, Kyung-Tae, Yoo, Kyung Ho, Oh, Chang-Hyun
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Sprache:eng
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