Plasma complement C3 levels are associated with insulin secretion independently of adiposity measures in non-diabetic individuals

Abstract Background and aims To evaluate if complement C3 is associated with insulin secretion, as suggested by recent in vitro studies, independently of confounders including adiposity measures. Methods and results 1010 nondiabetic subjects were stratified into quartiles according to complement C3...

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Veröffentlicht in:	Nutrition, metabolism, and cardiovascular diseases metabolism, and cardiovascular diseases, 2015-05, Vol.25 (5), p.510-517
Hauptverfasser:	Fiorentino, T.V, Hribal, M.L, Andreozzi, F, Perticone, M, Sciacqua, A, Perticone, F, Sesti, G
Format:	Artikel
Sprache:	eng
Schlagworte:	Adiposity Adult Body Mass Index Cardiovascular Complement C3 Complement C3 - analysis Complement C4 - analysis Complement system Cross-Sectional Studies Female Glucose homeostasis Glucose Tolerance Test Humans Insulin - blood Insulin - metabolism Insulin Resistance Insulin Secretion Insulin-Secreting Cells - metabolism Italy - epidemiology Male Metabolic Syndrome - epidemiology Metabolic Syndrome - etiology Middle Aged Obesity - blood Obesity - immunology Obesity - metabolism Obesity - physiopathology Overweight - blood Overweight - immunology Overweight - metabolism Overweight - physiopathology Risk Factors Subclinical inflammation Waist Circumference
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