"Anticardiolipin" autoantibodies recognize beta sub(2)-glycoprotein I in the absence of phospholipid. Importance of Ag density and bivalent binding

"Anticardiolipin" autoantibodies (aCL) bind to anionic phospholipids only in the presence of beta sub(2)-glycoprotein I ( beta 2GPI), a phospholipid-binding plasma protein. The exact role of beta 2GPI in the antigenic specificity of these autoantibodies is unclear, however. Experiments wer...

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Veröffentlicht in:	The Journal of immunology (1950) 1995-01, Vol.154 (2), p.954-960
Hauptverfasser:	Roubey, RAS, Eisenberg, R A, Harper, M F, Winfield, J B
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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