Role of secreted modular calcium-binding protein 1 (SMOC1) in transforming growth factor β signalling and angiogenesis

Secreted modular calcium-binding protein 1 (SMOC1) is a matricellular protein that potentially interferes with growth factor receptor signalling. The aim of this study was to determine how its expression is regulated in endothelial cells and its role in the regulation of endothelial cell function. S...

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Veröffentlicht in:	Cardiovascular research 2015-05, Vol.106 (2), p.284-294
Hauptverfasser:	Awwad, Khader, Hu, Jiong, Shi, Lei, Mangels, Nicole, Abdel Malik, Randa, Zippel, Nina, Fisslthaler, Beate, Eble, Johannes A, Pfeilschifter, Josef, Popp, Rüdiger, Fleming, Ingrid
Format:	Artikel
Sprache:	eng
Schlagworte:	Activin Receptors, Type I - metabolism Animals Cell Proliferation Endothelial Cells - metabolism Endothelium, Vascular - metabolism Mice, Inbred C57BL Mice, Transgenic Neovascularization, Physiologic - genetics Osteonectin - genetics Osteonectin - metabolism Receptors, Transforming Growth Factor beta - metabolism Signal Transduction Swine Transforming Growth Factor beta - metabolism
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