Definition of the transcription factor TdIF1 consensus‐binding sequence through genomewide mapping of its binding sites

TdIF1 was originally identified as a protein that directly binds to terminal deoxynucleotidyltransferase, TdT. Through in vitro selection assays (SELEX), we recently showed that TdIF1 recognizes both AT‐tract and a specific DNA sequence motif, 5′‐TGCATG‐3′, and can up‐regulate the expression of RAB2...

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Veröffentlicht in:	Genes to cells : devoted to molecular & cellular mechanisms 2015-03, Vol.20 (3), p.242-254
Hauptverfasser:	Koiwai, Kotaro, Kubota, Takashi, Watanabe, Nobuhisa, Hori, Katsutoshi, Koiwai, Osamu, Masai, Hisao
Format:	Artikel
Sprache:	eng
Schlagworte:	Binding Sites Carrier Proteins - chemistry Carrier Proteins - metabolism Cell Line Chromatin Immunoprecipitation Chromosome Mapping - methods Genes Humans Nuclear Proteins - chemistry Nuclear Proteins - metabolism Osteogenesis Response Elements - genetics Transcription factors Transcription Factors - chemistry Transcription Factors - metabolism
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