Antibody and clinical responses in volunteers to immunization with malaria peptide–diphtheria toxoid conjugates

SUMMARY Twenty residue peptides from the 185–200‐kD and 45‐kD merozoite surface antigens of the malaria parasite Plasmodium falciparum were covalently linked to diphtheria toxoid as a carrier and used to immunize human volunteers with aluminium hydroxide as an adjuvant. Significant antibody levels w...

Ausführliche Beschreibung