The effect of hydroxyl-containing dithiocarbamates on cisplatin-induced long-term renal dysfunction in Wistar rats

The possibility of a slow, longer term deterioration in renal function following the administration of cisplatin has been little studied in animal models. To obtain data on this we have examined renal function and histopathology at 30 days post i.p. cisplatin (5 mg/kg) treatment in female Wistar rat...

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Veröffentlicht in:Toxicology (Amsterdam) 1993-10, Vol.83 (1), p.79-91
Hauptverfasser: Reznik, Lev.V., Gambaryan, Stepan P., Jones, Mark M.
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Sprache:eng
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