Correlation of molecular parameters with lipoplex structure and transfection efficacy in pyridinium-based cationic lipids

Although promising, cationic lipid-mediated gene delivery can still be improved. In particular, significant improvements are needed in lipid design, lipoplex formulation and intracellular delivery. Pyridinium-based cationic amphiphiles represent a class of nonviral lipid vectors that have shown much...

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Veröffentlicht in:Molecular therapy 2013-09, Vol.21 (9), p.e46-e46
Hauptverfasser: Parvizi, Paria, Jubeli, Emile, Raju, Liji, Khalique, Nada Abdul, Almeer, Ahmed, Allam, Hebatalla, Manaa, Maryem Al, Larsen, Helge, Nicholson, David, Pungente, Michael D, Fyles, Thomas M
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Sprache:eng
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