Changes in the responsiveness of hypothalamic PK2 and PKR1 gene expression to fasting in developing male rats

Prokineticin (PK2) and its receptors (PKRs) are expressed in several regions of the central nervous system, including the hypothalamus. It has been reported that PK2 inhibits food intake via PKR1 and that the hypothalamic PK2 mRNA levels of adult rodents were reduced by food deprivation. However, so...

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Veröffentlicht in:	International journal of developmental neuroscience 2014-11, Vol.38 (1), p.87-90
Hauptverfasser:	Iwasa, Takeshi, Matsuzaki, Toshiya, Tungalagsuvd, Altankhuu, Munkhzaya, Munkhsaikhan, Kawami, Takako, Yamasaki, Mikio, Murakami, Masahiro, Kato, Takeshi, Kuwahara, Akira, Yasui, Toshiyuki, Irahara, Minoru
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Factors Analysis of Variance Animals Animals, Newborn Female Food deprivation Food Deprivation - physiology Gastrointestinal Hormones - genetics Gastrointestinal Hormones - metabolism Gene Expression Regulation, Developmental - physiology Hypothalamus Hypothalamus - growth & development Hypothalamus - metabolism Male Neuropeptides - genetics Neuropeptides - metabolism Pregnancy Prokineticin 2 Prokineticin receptor Rats Rats, Sprague-Dawley Receptors, G-Protein-Coupled - genetics Receptors, G-Protein-Coupled - metabolism Receptors, Peptide - genetics Receptors, Peptide - metabolism RNA, Messenger - metabolism Sex Factors
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