11 beta -HSD1 inhibition reduces atherosclerosis in mice by altering proinflammatory gene expression in the vasculature

11 beta -Hydroxysteroid dehydrogenase type 1 (11 beta -HSD1) is implicated in the etiology of metabolic syndrome. We previously showed that pharmacological inhibition of 11 beta -HSD1 ameliorated multiple facets of metabolic syndrome and attenuated atherosclerosis in ApoE-/- mice. However, the molec...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Physiological genomics 2013-01, Vol.45 (1), p.47-57
Hauptverfasser:	Luo, Mingjuan J, Thieringer, Rolf, Springer, Martin S, Wright, Samuel D, Hermanowski-Vosatka, Anne, Plump, Andrew, Balkovec, James M, Cheng, Kang, Ding, Gloria J, Kawka, Douglas W
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!