Prognostic marker analysis in pediatric intracranial ependymomas

Histologic grading methods dependent upon H&E staining review have not been shown to reliably predict survival in children with intracranial ependymomas due to the subjectivity of the analytical methods. We hypothesized that the immunohistochemical detection of MIB-1, Tenascin C, CD34, VEGF, and...

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Veröffentlicht in:	Journal of neuro-oncology 2015-04, Vol.122 (2), p.255-261
Hauptverfasser:	McLendon, Roger E., Lipp, Eric, Satterfield, Diane, Ehinger, Melissa, Austin, Alan, Fleming, Debra, Perkinson, Kathryn, Lefaivre, Michaela, Zagzag, David, Wiener, Benjamin, Gururangan, Sri, Fuchs, Herbert, Friedman, Henry S., Herndon, James E., Healy, Patrick
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Antibodies, Antinuclear - metabolism Antibodies, Monoclonal - metabolism Antigens, CD34 - metabolism Antigens, Neoplasm - metabolism Biomarkers, Tumor - metabolism Brain - metabolism Brain - pathology Brain - surgery Brain Neoplasms - metabolism Brain Neoplasms - pathology Brain Neoplasms - surgery Carbonic Anhydrase IX Carbonic Anhydrases - metabolism Child Child, Preschool Ependymoma - metabolism Ependymoma - pathology Ependymoma - surgery Female Follow-Up Studies Humans Immunohistochemistry Infant Kaplan-Meier Estimate Laboratory Investigation Male Medicine Medicine & Public Health Neoplasm Grading Neurology Oncology Prognosis Retrospective Studies Tenascin - metabolism Vascular Endothelial Growth Factor A - metabolism
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