Aberrant Behavioral Sensitization by Methamphetamine in Junctophilin-Deficient Mice

Junctophilins (JPs) expressed in the endoplasmic/sarcoplasmic reticulum (ER/SR) interact with the plasma membrane, thereby constructing junctional membrane complexes (JMC). We here reported that double-knockout mice lacking both JP3 and JP4 (JP-DKO mice) exhibit aberrant synaptic plasticity in the c...

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Veröffentlicht in:	Molecular neurobiology 2015-04, Vol.51 (2), p.533-542
Hauptverfasser:	Moriguchi, Shigeki, Nishi, Miyuki, Sasaki, Yuzuru, Takeshima, Hiroshi, Fukunaga, Kohji
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biomedical and Life Sciences Biomedicine Cell Biology Corpus Striatum - drug effects Corpus Striatum - metabolism Dose-Response Relationship, Drug Membrane Proteins - deficiency Methamphetamine Methamphetamine - toxicity Mice Mice, Inbred C57BL Mice, Knockout Motor Activity - drug effects Motor Activity - physiology Neurobiology Neurology Neurosciences Organ Culture Techniques Rodents
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