Enhancement of ICRP's Lung Deposition Model for Pathogenic Bioaerosols
Terrorist attacks using pathogenic bioaerosols pose a significant public-health threat. Modeling the risk associated with such attacks is valuable from the standpoint of disaster preparedness. To attain greater flexibility in bioterrorism risk modeling, we have developed an open-source lung depositi...
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| Veröffentlicht in: | Aerosol science and technology 2014-12, Vol.48 (12), p.1226-1235 |
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| container_title | Aerosol science and technology |
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| creator | Guha, Suvajyoti Hariharan, Prasanna Myers, Matthew R. |
| description | Terrorist attacks using pathogenic bioaerosols pose a significant public-health threat. Modeling the risk associated with such attacks is valuable from the standpoint of disaster preparedness. To attain greater flexibility in bioterrorism risk modeling, we have developed an open-source lung deposition code based on the International Committee for Radiological Protection (ICRP) Publication 66 (ICRP 1994). This article describes modifications to ICRP's lung deposition model to fit the bioaerosol context and discusses the impact of exposure from a few monodisperse pathogenic toxins such as botulinum toxin, influenza virus, and Bacillus anthracis to infants and adults. As most existing commercial lung deposition codes are not open-source, this code provides users a platform template that can be modified to meet their needs. |
| doi_str_mv | 10.1080/02786826.2014.975334 |
| format | Article |
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Modeling the risk associated with such attacks is valuable from the standpoint of disaster preparedness. To attain greater flexibility in bioterrorism risk modeling, we have developed an open-source lung deposition code based on the International Committee for Radiological Protection (ICRP) Publication 66 (ICRP 1994). This article describes modifications to ICRP's lung deposition model to fit the bioaerosol context and discusses the impact of exposure from a few monodisperse pathogenic toxins such as botulinum toxin, influenza virus, and Bacillus anthracis to infants and adults. 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Modeling the risk associated with such attacks is valuable from the standpoint of disaster preparedness. To attain greater flexibility in bioterrorism risk modeling, we have developed an open-source lung deposition code based on the International Committee for Radiological Protection (ICRP) Publication 66 (ICRP 1994). This article describes modifications to ICRP's lung deposition model to fit the bioaerosol context and discusses the impact of exposure from a few monodisperse pathogenic toxins such as botulinum toxin, influenza virus, and Bacillus anthracis to infants and adults. 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| source | IngentaConnect Free/Open Access Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Free Full-Text Journals in Chemistry |
| subjects | Adults Aerosols Airborne microorganisms Bacillus anthracis Bioaerosols Biological & chemical terrorism Biological & chemical weapons Biological and medical sciences Bioterrorism Chemistry Colloidal state and disperse state Deposition Disaster management Emergency preparedness Exact sciences and technology Freeware General and physical chemistry Health risks Human exposure Infants Influenza virus Lungs Mathematical models Medical sciences Miscellaneous Public health Public health. Hygiene Public health. Hygiene-occupational medicine Radiology Risk Source code Terrorism Threat models Toxins Viruses |
| title | Enhancement of ICRP's Lung Deposition Model for Pathogenic Bioaerosols |
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