Simulated games activity vs continuous running exercise: A novel comparison of the glycemic and metabolic responses in T1DM patients
To compare the glycemic and metabolic responses to simulated intermittent games activity and continuous running exercise in type 1 diabetes. Nine patients (seven male, two female; 35 ± 4 years; HbA1c 8.1 ± 0.2%/65 ± 2 mmol/mol) treated on a basal‐bolus regimen completed two main trials, a continuous...
Gespeichert in:
| Veröffentlicht in: | Scandinavian journal of medicine & science in sports 2015-04, Vol.25 (2), p.216-222 |
|---|---|
| Hauptverfasser: | , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 222 |
|---|---|
| container_issue | 2 |
| container_start_page | 216 |
| container_title | Scandinavian journal of medicine & science in sports |
| container_volume | 25 |
| creator | Campbell, M. D. West, D. J. Bain, S. C. Kingsley, M. I. C. Foley, P. Kilduff, L. Turner, D. Gray, B. Stephens, J. W. Bracken, R. M. |
| description | To compare the glycemic and metabolic responses to simulated intermittent games activity and continuous running exercise in type 1 diabetes. Nine patients (seven male, two female; 35 ± 4 years; HbA1c 8.1 ± 0.2%/65 ± 2 mmol/mol) treated on a basal‐bolus regimen completed two main trials, a continuous treadmill run (CON) or an intermittent running protocol (INT). Patients arrived to the laboratory fasted at ∼ 08:00 h, replicating their usual pre‐exercise meal and administering a 50% reduced dose of rapid‐acting insulin before exercising. Blood glucose (BG), K+, Na++, pH, triglycerides, serum cortisol and NEFA were measured at baseline and for 60 min post‐exercise. Interstitial glucose was measured for a further 23 h under free‐living conditions. Following exercise, BG declined under both conditions but was less under INT (INT −1.1 ± 1.4 vs CON −5.3 ± 0.4 mmol/L, P = 0.037), meaning more patients experienced hypoglycemia (BG ≤ 3.5 mmol/L; CON n = 3 vs INT n = 2) but less hyperglycemia (BG ≥ 10.9 mmol/L; CON n = 0 vs INT n = 6) under CON. Blood lactate was significantly greater, and pH lower, with a temporal delay in K+ under INT (P |
| doi_str_mv | 10.1111/sms.12192 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1673384541</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1667352105</sourcerecordid><originalsourceid>FETCH-LOGICAL-c5292-e5123800a6b90f2a6553ab358dbd1e3763f16c056e62f15c4a1c36a08ea1c63b3</originalsourceid><addsrcrecordid>eNqN0U1v1DAQBmALgehSOPAHkCUu5ZDWH7GTcKsKLaC2CO0iuFmOM1lcEjvYztK988Nx2bYHJCR8sS0989qjQeg5JYc0r6M4xkPKaMMeoAWVhBSk5vVDtCANEUVF63oPPYnxihBaNaV4jPZYKRpOmVigX0s7zoNO0OG1HiFibZLd2LTFm4iNd8m62c8Rh9k569YYriEYG-E1PsbOb2DIaJx0sNE77HucvgFeD1sDozVYuw6PkHTrh3wLECfvYn7DOryiby7wpJMFl-JT9KjXQ4Rnt_s--nz6dnXyrjj_ePb-5Pi8MII1rABBGa8J0bJtSM-0FILrlou6azsKvJK8p9IQIUGyngpTamq41KSGfJC85fvoYJc7Bf9jhpjUaKOBYdAOcpOKyorzuhQl_Q-arWCUiExf_kWv_BxcbuRGifz1hpZZvdopE3yMAXo1BTvqsFWUqJspqjxF9WeK2b64TZzbEbp7eTe2DI524KcdYPvvJLW8WN5FFrsKGxNc31fo8F3lRiqhvlyeqVO2uvz66QNXNf8NHn215A</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1665529914</pqid></control><display><type>article</type><title>Simulated games activity vs continuous running exercise: A novel comparison of the glycemic and metabolic responses in T1DM patients</title><source>MEDLINE</source><source>Access via Wiley Online Library</source><creator>Campbell, M. D. ; West, D. J. ; Bain, S. C. ; Kingsley, M. I. C. ; Foley, P. ; Kilduff, L. ; Turner, D. ; Gray, B. ; Stephens, J. W. ; Bracken, R. M.</creator><creatorcontrib>Campbell, M. D. ; West, D. J. ; Bain, S. C. ; Kingsley, M. I. C. ; Foley, P. ; Kilduff, L. ; Turner, D. ; Gray, B. ; Stephens, J. W. ; Bracken, R. M.</creatorcontrib><description>To compare the glycemic and metabolic responses to simulated intermittent games activity and continuous running exercise in type 1 diabetes. Nine patients (seven male, two female; 35 ± 4 years; HbA1c 8.1 ± 0.2%/65 ± 2 mmol/mol) treated on a basal‐bolus regimen completed two main trials, a continuous treadmill run (CON) or an intermittent running protocol (INT). Patients arrived to the laboratory fasted at ∼ 08:00 h, replicating their usual pre‐exercise meal and administering a 50% reduced dose of rapid‐acting insulin before exercising. Blood glucose (BG), K+, Na++, pH, triglycerides, serum cortisol and NEFA were measured at baseline and for 60 min post‐exercise. Interstitial glucose was measured for a further 23 h under free‐living conditions. Following exercise, BG declined under both conditions but was less under INT (INT −1.1 ± 1.4 vs CON −5.3 ± 0.4 mmol/L, P = 0.037), meaning more patients experienced hypoglycemia (BG ≤ 3.5 mmol/L; CON n = 3 vs INT n = 2) but less hyperglycemia (BG ≥ 10.9 mmol/L; CON n = 0 vs INT n = 6) under CON. Blood lactate was significantly greater, and pH lower, with a temporal delay in K+ under INT (P < 0.05). No conditional differences were observed in other measures during this time, or in interstitial glucose concentrations during the remaining 23 h after exercise. Simulated games activity carries a lower risk of early, but not late‐onset hypoglycemia than continuous running exercise in type 1 diabetes.</description><identifier>ISSN: 0905-7188</identifier><identifier>EISSN: 1600-0838</identifier><identifier>DOI: 10.1111/sms.12192</identifier><identifier>PMID: 24593125</identifier><language>eng</language><publisher>Denmark: Blackwell Publishing Ltd</publisher><subject>Adult ; Biomarkers - blood ; Blood Glucose - metabolism ; Diabetes ; Diabetes Mellitus, Type 1 - complications ; Diabetes Mellitus, Type 1 - metabolism ; Diabetes Mellitus, Type 1 - therapy ; Exercise ; Exercise Therapy - adverse effects ; Exercise Therapy - methods ; Female ; Games, Recreational ; Glucose ; Humans ; Hyperglycemia - blood ; Hyperglycemia - diagnosis ; Hyperglycemia - etiology ; Hyperglycemia - prevention & control ; Hypoglycemia - blood ; Hypoglycemia - diagnosis ; Hypoglycemia - etiology ; Hypoglycemia - prevention & control ; intermittent running ; Lactic Acid - blood ; Male ; Metabolism ; post-exercise hypoglycemia ; Random Allocation ; Running - physiology ; Simulation ; T1DM</subject><ispartof>Scandinavian journal of medicine & science in sports, 2015-04, Vol.25 (2), p.216-222</ispartof><rights>2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd</rights><rights>2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.</rights><rights>Copyright © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c5292-e5123800a6b90f2a6553ab358dbd1e3763f16c056e62f15c4a1c36a08ea1c63b3</citedby><cites>FETCH-LOGICAL-c5292-e5123800a6b90f2a6553ab358dbd1e3763f16c056e62f15c4a1c36a08ea1c63b3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fsms.12192$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fsms.12192$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1417,27924,27925,45574,45575</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24593125$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Campbell, M. D.</creatorcontrib><creatorcontrib>West, D. J.</creatorcontrib><creatorcontrib>Bain, S. C.</creatorcontrib><creatorcontrib>Kingsley, M. I. C.</creatorcontrib><creatorcontrib>Foley, P.</creatorcontrib><creatorcontrib>Kilduff, L.</creatorcontrib><creatorcontrib>Turner, D.</creatorcontrib><creatorcontrib>Gray, B.</creatorcontrib><creatorcontrib>Stephens, J. W.</creatorcontrib><creatorcontrib>Bracken, R. M.</creatorcontrib><title>Simulated games activity vs continuous running exercise: A novel comparison of the glycemic and metabolic responses in T1DM patients</title><title>Scandinavian journal of medicine & science in sports</title><addtitle>Scand J Med Sci Sports</addtitle><description>To compare the glycemic and metabolic responses to simulated intermittent games activity and continuous running exercise in type 1 diabetes. Nine patients (seven male, two female; 35 ± 4 years; HbA1c 8.1 ± 0.2%/65 ± 2 mmol/mol) treated on a basal‐bolus regimen completed two main trials, a continuous treadmill run (CON) or an intermittent running protocol (INT). Patients arrived to the laboratory fasted at ∼ 08:00 h, replicating their usual pre‐exercise meal and administering a 50% reduced dose of rapid‐acting insulin before exercising. Blood glucose (BG), K+, Na++, pH, triglycerides, serum cortisol and NEFA were measured at baseline and for 60 min post‐exercise. Interstitial glucose was measured for a further 23 h under free‐living conditions. Following exercise, BG declined under both conditions but was less under INT (INT −1.1 ± 1.4 vs CON −5.3 ± 0.4 mmol/L, P = 0.037), meaning more patients experienced hypoglycemia (BG ≤ 3.5 mmol/L; CON n = 3 vs INT n = 2) but less hyperglycemia (BG ≥ 10.9 mmol/L; CON n = 0 vs INT n = 6) under CON. Blood lactate was significantly greater, and pH lower, with a temporal delay in K+ under INT (P < 0.05). No conditional differences were observed in other measures during this time, or in interstitial glucose concentrations during the remaining 23 h after exercise. Simulated games activity carries a lower risk of early, but not late‐onset hypoglycemia than continuous running exercise in type 1 diabetes.</description><subject>Adult</subject><subject>Biomarkers - blood</subject><subject>Blood Glucose - metabolism</subject><subject>Diabetes</subject><subject>Diabetes Mellitus, Type 1 - complications</subject><subject>Diabetes Mellitus, Type 1 - metabolism</subject><subject>Diabetes Mellitus, Type 1 - therapy</subject><subject>Exercise</subject><subject>Exercise Therapy - adverse effects</subject><subject>Exercise Therapy - methods</subject><subject>Female</subject><subject>Games, Recreational</subject><subject>Glucose</subject><subject>Humans</subject><subject>Hyperglycemia - blood</subject><subject>Hyperglycemia - diagnosis</subject><subject>Hyperglycemia - etiology</subject><subject>Hyperglycemia - prevention & control</subject><subject>Hypoglycemia - blood</subject><subject>Hypoglycemia - diagnosis</subject><subject>Hypoglycemia - etiology</subject><subject>Hypoglycemia - prevention & control</subject><subject>intermittent running</subject><subject>Lactic Acid - blood</subject><subject>Male</subject><subject>Metabolism</subject><subject>post-exercise hypoglycemia</subject><subject>Random Allocation</subject><subject>Running - physiology</subject><subject>Simulation</subject><subject>T1DM</subject><issn>0905-7188</issn><issn>1600-0838</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqN0U1v1DAQBmALgehSOPAHkCUu5ZDWH7GTcKsKLaC2CO0iuFmOM1lcEjvYztK988Nx2bYHJCR8sS0989qjQeg5JYc0r6M4xkPKaMMeoAWVhBSk5vVDtCANEUVF63oPPYnxihBaNaV4jPZYKRpOmVigX0s7zoNO0OG1HiFibZLd2LTFm4iNd8m62c8Rh9k569YYriEYG-E1PsbOb2DIaJx0sNE77HucvgFeD1sDozVYuw6PkHTrh3wLECfvYn7DOryiby7wpJMFl-JT9KjXQ4Rnt_s--nz6dnXyrjj_ePb-5Pi8MII1rABBGa8J0bJtSM-0FILrlou6azsKvJK8p9IQIUGyngpTamq41KSGfJC85fvoYJc7Bf9jhpjUaKOBYdAOcpOKyorzuhQl_Q-arWCUiExf_kWv_BxcbuRGifz1hpZZvdopE3yMAXo1BTvqsFWUqJspqjxF9WeK2b64TZzbEbp7eTe2DI524KcdYPvvJLW8WN5FFrsKGxNc31fo8F3lRiqhvlyeqVO2uvz66QNXNf8NHn215A</recordid><startdate>201504</startdate><enddate>201504</enddate><creator>Campbell, M. D.</creator><creator>West, D. J.</creator><creator>Bain, S. C.</creator><creator>Kingsley, M. I. C.</creator><creator>Foley, P.</creator><creator>Kilduff, L.</creator><creator>Turner, D.</creator><creator>Gray, B.</creator><creator>Stephens, J. W.</creator><creator>Bracken, R. M.</creator><general>Blackwell Publishing Ltd</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TS</scope><scope>K9.</scope><scope>7X8</scope></search><sort><creationdate>201504</creationdate><title>Simulated games activity vs continuous running exercise: A novel comparison of the glycemic and metabolic responses in T1DM patients</title><author>Campbell, M. D. ; West, D. J. ; Bain, S. C. ; Kingsley, M. I. C. ; Foley, P. ; Kilduff, L. ; Turner, D. ; Gray, B. ; Stephens, J. W. ; Bracken, R. M.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c5292-e5123800a6b90f2a6553ab358dbd1e3763f16c056e62f15c4a1c36a08ea1c63b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Adult</topic><topic>Biomarkers - blood</topic><topic>Blood Glucose - metabolism</topic><topic>Diabetes</topic><topic>Diabetes Mellitus, Type 1 - complications</topic><topic>Diabetes Mellitus, Type 1 - metabolism</topic><topic>Diabetes Mellitus, Type 1 - therapy</topic><topic>Exercise</topic><topic>Exercise Therapy - adverse effects</topic><topic>Exercise Therapy - methods</topic><topic>Female</topic><topic>Games, Recreational</topic><topic>Glucose</topic><topic>Humans</topic><topic>Hyperglycemia - blood</topic><topic>Hyperglycemia - diagnosis</topic><topic>Hyperglycemia - etiology</topic><topic>Hyperglycemia - prevention & control</topic><topic>Hypoglycemia - blood</topic><topic>Hypoglycemia - diagnosis</topic><topic>Hypoglycemia - etiology</topic><topic>Hypoglycemia - prevention & control</topic><topic>intermittent running</topic><topic>Lactic Acid - blood</topic><topic>Male</topic><topic>Metabolism</topic><topic>post-exercise hypoglycemia</topic><topic>Random Allocation</topic><topic>Running - physiology</topic><topic>Simulation</topic><topic>T1DM</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Campbell, M. D.</creatorcontrib><creatorcontrib>West, D. J.</creatorcontrib><creatorcontrib>Bain, S. C.</creatorcontrib><creatorcontrib>Kingsley, M. I. C.</creatorcontrib><creatorcontrib>Foley, P.</creatorcontrib><creatorcontrib>Kilduff, L.</creatorcontrib><creatorcontrib>Turner, D.</creatorcontrib><creatorcontrib>Gray, B.</creatorcontrib><creatorcontrib>Stephens, J. W.</creatorcontrib><creatorcontrib>Bracken, R. M.</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Physical Education Index</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><jtitle>Scandinavian journal of medicine & science in sports</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Campbell, M. D.</au><au>West, D. J.</au><au>Bain, S. C.</au><au>Kingsley, M. I. C.</au><au>Foley, P.</au><au>Kilduff, L.</au><au>Turner, D.</au><au>Gray, B.</au><au>Stephens, J. W.</au><au>Bracken, R. M.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Simulated games activity vs continuous running exercise: A novel comparison of the glycemic and metabolic responses in T1DM patients</atitle><jtitle>Scandinavian journal of medicine & science in sports</jtitle><addtitle>Scand J Med Sci Sports</addtitle><date>2015-04</date><risdate>2015</risdate><volume>25</volume><issue>2</issue><spage>216</spage><epage>222</epage><pages>216-222</pages><issn>0905-7188</issn><eissn>1600-0838</eissn><abstract>To compare the glycemic and metabolic responses to simulated intermittent games activity and continuous running exercise in type 1 diabetes. Nine patients (seven male, two female; 35 ± 4 years; HbA1c 8.1 ± 0.2%/65 ± 2 mmol/mol) treated on a basal‐bolus regimen completed two main trials, a continuous treadmill run (CON) or an intermittent running protocol (INT). Patients arrived to the laboratory fasted at ∼ 08:00 h, replicating their usual pre‐exercise meal and administering a 50% reduced dose of rapid‐acting insulin before exercising. Blood glucose (BG), K+, Na++, pH, triglycerides, serum cortisol and NEFA were measured at baseline and for 60 min post‐exercise. Interstitial glucose was measured for a further 23 h under free‐living conditions. Following exercise, BG declined under both conditions but was less under INT (INT −1.1 ± 1.4 vs CON −5.3 ± 0.4 mmol/L, P = 0.037), meaning more patients experienced hypoglycemia (BG ≤ 3.5 mmol/L; CON n = 3 vs INT n = 2) but less hyperglycemia (BG ≥ 10.9 mmol/L; CON n = 0 vs INT n = 6) under CON. Blood lactate was significantly greater, and pH lower, with a temporal delay in K+ under INT (P < 0.05). No conditional differences were observed in other measures during this time, or in interstitial glucose concentrations during the remaining 23 h after exercise. Simulated games activity carries a lower risk of early, but not late‐onset hypoglycemia than continuous running exercise in type 1 diabetes.</abstract><cop>Denmark</cop><pub>Blackwell Publishing Ltd</pub><pmid>24593125</pmid><doi>10.1111/sms.12192</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0905-7188 |
| ispartof | Scandinavian journal of medicine & science in sports, 2015-04, Vol.25 (2), p.216-222 |
| issn | 0905-7188 1600-0838 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1673384541 |
| source | MEDLINE; Access via Wiley Online Library |
| subjects | Adult Biomarkers - blood Blood Glucose - metabolism Diabetes Diabetes Mellitus, Type 1 - complications Diabetes Mellitus, Type 1 - metabolism Diabetes Mellitus, Type 1 - therapy Exercise Exercise Therapy - adverse effects Exercise Therapy - methods Female Games, Recreational Glucose Humans Hyperglycemia - blood Hyperglycemia - diagnosis Hyperglycemia - etiology Hyperglycemia - prevention & control Hypoglycemia - blood Hypoglycemia - diagnosis Hypoglycemia - etiology Hypoglycemia - prevention & control intermittent running Lactic Acid - blood Male Metabolism post-exercise hypoglycemia Random Allocation Running - physiology Simulation T1DM |
| title | Simulated games activity vs continuous running exercise: A novel comparison of the glycemic and metabolic responses in T1DM patients |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-29T16%3A52%3A09IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Simulated%20games%20activity%20vs%20continuous%20running%20exercise:%20A%20novel%20comparison%20of%20the%20glycemic%20and%20metabolic%20responses%20in%20T1DM%20patients&rft.jtitle=Scandinavian%20journal%20of%20medicine%20&%20science%20in%20sports&rft.au=Campbell,%20M.%20D.&rft.date=2015-04&rft.volume=25&rft.issue=2&rft.spage=216&rft.epage=222&rft.pages=216-222&rft.issn=0905-7188&rft.eissn=1600-0838&rft_id=info:doi/10.1111/sms.12192&rft_dat=%3Cproquest_cross%3E1667352105%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1665529914&rft_id=info:pmid/24593125&rfr_iscdi=true |