Aggravation of left ventricular dysfunction in patients with biopsy-proven cardiac human herpesvirus A and B infection

Aggravation of left ventricular dysfunction in patients with biopsy-proven cardiac human herpesvirus A and B infection

Highlights • We evaluated patients with cardiac HHV-6 A and B infection in EMBs. • Persistence of cardiac HHV-6 A and B genomes was associated with LV-dysfunction. • Hemodynamic parameters improved in association with cardiac HHV-6 A/B clearance. • Data provide evidence of a myocardial involvement i...

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Veröffentlicht in:Journal of clinical virology 2015-02, Vol.63, p.1-5
Hauptverfasser: Escher, F, Kühl, U, Gross, U, Westermann, D, Poller, W, Tschöpe, C, Lassner, D, Schultheiss, H.-P
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Aged
Allergy and Immunology
Biopsy
Blood - virology
Cardiomyopathies - pathology
Cardiomyopathies - virology
Female
Heart
Heart - virology
Heart failure
Herpesvirus 6, Human - classification
Herpesvirus 6, Human - isolation & purification
HHV6
Human herpesvirus 6
Humans
Immunohistochemistry
Infectious Disease
Inflammatory cardiomyopathy
Male
Middle Aged
Myocardium - pathology
Prognosis
Prospective Studies
Roseolovirus Infections - complications
Roseolovirus Infections - virology
Ventricular Dysfunction, Left - physiopathology
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Zusammenfassung:Highlights • We evaluated patients with cardiac HHV-6 A and B infection in EMBs. • Persistence of cardiac HHV-6 A and B genomes was associated with LV-dysfunction. • Hemodynamic parameters improved in association with cardiac HHV-6 A/B clearance. • Data provide evidence of a myocardial involvement in patients with cardiac HHV-6 A and B infection.
ISSN:1386-6532
1873-5967
DOI:10.1016/j.jcv.2014.11.026