Higher antiviral response of RIG-I through enhancing RIG-I/MAVS-mediated signaling by its long insertion variant in zebrafish

As an intracellular pattern recognition receptor (PRR), the retinoic acid-inducible gene-I (RIG-I) is responsible for the recognition of cytosolic viral nucleic acids and the production of type I interferons (IFNs). In the present study, an insertion variant of RIG-I with 38 amino acids inserted in...

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Veröffentlicht in:Fish & shellfish immunology 2015-03, Vol.43 (1), p.13-24
Hauptverfasser: Zou, Peng Fei, Chang, Ming Xian, Li, Ying, Huan Zhang, Shu, Fu, Jian Ping, Chen, Shan Nan, Nie, Pin
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Sprache:eng
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