Similar serotonin-2A receptor binding in rats with different coping styles or levels of aggression

ABSTRACT Individual differences in coping style emerge as a function of underlying variability in the activation of a mesocorticolimbic brain circuitry. Particularly serotonin seems to play an important role. For this reason, we assessed serotonin‐2A receptor (5‐HT2AR) binding in the brain of rats w...

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Veröffentlicht in:	Synapse (New York, N.Y.) N.Y.), 2015-04, Vol.69 (4), p.226-232
Hauptverfasser:	Visser, Anniek K.D., Ettrup, Anders, Klein, Anders B., van Waarde, Aren, Bosker, Fokko J., Meerlo, Peter, Knudsen, Gitte M., de Boer, Sietse F.
Format:	Artikel
Sprache:	eng
Schlagworte:	5-HT2A receptor Adaptation, Psychological - drug effects Aggression - physiology agonist Animals antagonist Avoidance Learning - physiology Benzylamines - pharmacokinetics binding assays Brain - drug effects Brain - metabolism Cimbi-36 Fluorobenzenes - pharmacokinetics frontal cortex hippocampus individual response Male MDL-100907 Phenethylamines - pharmacokinetics Piperidines - pharmacokinetics Protein Binding - drug effects Protein Binding - genetics Rats Rats, Inbred Strains Receptor, Serotonin, 5-HT2A - metabolism Serotonin - metabolism Serotonin Antagonists - pharmacokinetics Serotonin Receptor Agonists - pharmacokinetics stress Tritium - pharmacokinetics
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