Killer cell immunoglobulin-like receptor (KIR) gene diversity in a population naturally exposed to malaria in Porto Velho, Northern Brazil

Killer cell immunoglobulin‐like receptors (KIR) are expressed mainly in natural killer cells and specifically recognize human leukocyte antigen (HLA) class I molecules. The repertoire of KIR genes and KIR–HLA pairs is known to play a key role in the susceptibilities to and the outcomes of several di...

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Veröffentlicht in:	Tissue antigens 2015-03, Vol.85 (3), p.190-199
Hauptverfasser:	Perce-da-Silva, D. S., Silva, L. A., Lima-Junior, J. C., Cardoso-Oliveira, J., Ribeiro-Alves, M., Santos, F., Porto, L. C. M. S., Oliveira-Ferreira, J., Banic, D. M.
Format:	Artikel
Sprache:	eng
Schlagworte:	African Continental Ancestry Group Alleles Brazil Brazil - ethnology European Continental Ancestry Group Gene Expression Gene Frequency Genotype Hispanic Americans HLA Antigens - classification HLA Antigens - genetics HLA Antigens - immunology human leukocyte antigen Humans killer immunoglobulin-like receptors malaria Malaria, Falciparum - ethnology Malaria, Falciparum - genetics Malaria, Falciparum - immunology Malaria, Falciparum - parasitology Malaria, Vivax - ethnology Malaria, Vivax - genetics Malaria, Vivax - immunology Malaria, Vivax - parasitology Plasmodium falciparum - isolation & purification Plasmodium vivax - isolation & purification Polymorphism, Genetic Principal Component Analysis Receptors, KIR - classification Receptors, KIR - genetics Receptors, KIR - immunology
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