Influence of X-rays on early response gene expression in rat astrocytes and brain tumour cell lines

The effects of ionizing radiation on c-fos, c-jun and jun-B mRNA levels were determined in cultures of rat perinatal type 1 astrocytes and two rat brain tumour cell lines, 175A and 9L. In astrocyte cultures X-ray doses as low as 1 Gy induced the expression of c-fos and jun-B but had essentially no e...

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Veröffentlicht in:	International journal of radiation biology 1994-12, Vol.66 (6), p.739-746
Hauptverfasser:	VRDOLJAK, E, BORCHARDT, P. E, BILL, C. A, STEPHENS, L. C, TOFILON, P. J
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Astrocytes - metabolism Biological and medical sciences Brain Neoplasms - metabolism Fundamental and applied biological sciences. Psychology Gene Expression - drug effects Gene Expression - radiation effects Genes, fos - drug effects Genes, fos - radiation effects Genes, jun - drug effects Genes, jun - radiation effects Molecular and cellular biology Molecular genetics Mutagenesis. Repair Radiation Dosage Radiation, Ionizing Rats RNA, Messenger - analysis Tetradecanoylphorbol Acetate - pharmacology Tumor Cells, Cultured
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