Cryopreservation of microencapsulated murine mesenchymal stem cells genetically engineered to secrete erythropoietin

[Display omitted] The ability to cryopreserve and store for long term the structure and function of therapeutic cells and tissues plays a pivotal role in clinical medicine. In fact, it is an essential pre-requisite for the commercial and clinical application of stem cells since preserves cells at lo...

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Veröffentlicht in:	International journal of pharmaceutics 2015-05, Vol.485 (1-2), p.15-24
Hauptverfasser:	Gurruchaga, Haritz, Ciriza, Jesús, Saenz del Burgo, Laura, Rodriguez-Madoz, Juan Roberto, Santos, Edorta, Prosper, Felipe, Hernández, Rosa María, Orive, Gorka, Pedraz, Jose Luis
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Shape - drug effects Cell Survival - drug effects Cells, Cultured Cryopreservation Cryoprotective Agents - pharmacology Dimethyl Sulfoxide - pharmacology Dose-Response Relationship, Drug Erythropoietin - genetics Erythropoietin - metabolism Erythropoietin - secretion Glycerol - pharmacology Hematocrit Hematopoiesis Mesenchymal Stem Cell Transplantation Mesenchymal stem cells Mesenchymal Stromal Cells - drug effects Mesenchymal Stromal Cells - metabolism Mesenchymal Stromal Cells - secretion Mice Mice, Inbred BALB C Microencapsulation Nanotechnology Time Factors Transfection Trehalose - pharmacology
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