Hyponatremia as a powerful prognostic predictor for Japanese patients with clear cell renal cell carcinoma treated with a tyrosine kinase inhibitor

Background We aimed to evaluate the prognostic significance of hyponatremia in patients with metastatic clear cell renal cell carcinoma (RCC) treated with a tyrosine kinase inhibitor (TKI). Methods This study included a total of 209 consecutive Japanese patients undergoing radical nephrectomy who we...

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Veröffentlicht in:	International journal of clinical oncology 2015-04, Vol.20 (2), p.351-357
Hauptverfasser:	Furukawa, Junya, Miyake, Hideaki, Kusuda, Yuji, Fujisawa, Masato
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Antineoplastic Agents - therapeutic use C-Reactive Protein - metabolism Cancer Research Carcinoma, Renal Cell - complications Carcinoma, Renal Cell - secondary Carcinoma, Renal Cell - therapy Chemotherapy, Adjuvant Disease-Free Survival Drug therapy Female Humans Hyponatremia - blood Hyponatremia - complications Indoles - therapeutic use Inhibitor drugs Japan Kidney cancer Kidney Neoplasms - complications Kidney Neoplasms - pathology Kidney Neoplasms - therapy Male Medical prognosis Medicine Medicine & Public Health Middle Aged Nephrectomy Niacinamide - analogs & derivatives Niacinamide - therapeutic use Oncology Original Article Phenylurea Compounds - therapeutic use Protein Kinase Inhibitors - therapeutic use Pyrroles - therapeutic use Retrospective Studies Risk Factors Serum Albumin - metabolism Sodium - blood Surgical Oncology Survival Rate
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