Morphologic and functional alterations of mucosal T cells by cholera toxin and its B subunit

Despite the mucosal immunogenicity and adjuvanticity in vivo of cholera toxin (CT), both CT and CT B subunit are strong inhibitors of T cell activation in vitro. This study asked whether such T cell inhibition is relevant to the mucosal effects of CT in vivo. The activation of T cells pulsed in vitr...

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Veröffentlicht in:	The Journal of immunology (1950) 1995-02, Vol.154 (3), p.1032-1040
Hauptverfasser:	Elson, CO, Holland, SP, Dertzbaugh, MT, Cuff, CF, Anderson, AO
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals CD4-Positive T-Lymphocytes - drug effects CD8-Positive T-Lymphocytes - drug effects Cells, Cultured Cholera Toxin - toxicity Enzyme-Linked Immunosorbent Assay Female Flow Cytometry Immunoenzyme Techniques Intestinal Mucosa - immunology Lymphocyte Activation - immunology Mice Mice, Inbred C57BL Mice, Inbred Strains Vibrio cholerae
Online-Zugang:	Volltext
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