Correlation of neuroactive steroid modulation of [ super(35)S]t-butylbicyclophosphorothionate and [ super(3)H]flunitrazepam binding and gamma -aminobutyric acid sub(A) receptor function

Neuroactive steroids, including endogenously occurring metabolites of progesterone and deoxycorticosterone as well as their synthetic derivatives, are positive allosteric modulators of the gamma -aminobutyric acid (GABA) sub(A) receptor complex. They inhibit the binding of [ super(35)S]t-butylbicycl...

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Veröffentlicht in:	Molecular pharmacology 1994-01, Vol.46 (5), p.977-985
Hauptverfasser:	Hawkinson, JE, Kimbrough, CL, Belelli, D, Lambert, J J, Purdy, R H, Lan, N C
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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