Synergistic antiproliferative activity of suramin and alpha 2A-interferon against human colorectal adenocarcinoma cell lines: in vitro studies

Suramin, a polysulphonated naphthylurea proven to be an effective anticancer agent against selected tumours, and alpha 2A-interferon (alpha 2A-IFN) were investigated for their combined effects on HCT-8, HCT-15, CL-D, SW-480 and SW-620 human colorectal adenocarcinoma cell lines. All lines were sensit...

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Veröffentlicht in:	European journal of cancer (1990) 1994, Vol.30A (4), p.516-520
Hauptverfasser:	Falcone, A, Danesi, R, Zaccaro, L, Pieracci, D, Pfanner, E, Cianci, C, Andreuccetti, M, Malvaldi, G, Del Tacca, M, Conte, P F
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - therapy Cell Division - drug effects Cell Survival - drug effects Colorectal Neoplasms - therapy Dose-Response Relationship, Drug Drug Screening Assays, Antitumor Drug Synergism Humans Interferon alpha-2 Interferon-alpha - pharmacology Recombinant Proteins Suramin - pharmacology Tumor Cells, Cultured - drug effects
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