Bradykinin excites rat sympathetic neurons by inhibition of M current through a mechanism involving B sub(2) receptors and G sub( alpha q/11)

Bradykinin (BK) is a peptide mediator released in inflammation that potently excites sympathetic neurons. We have studied the mechanism of this excitation in dissociated rat sympathetic neurons and found that at low nanomolar concentrations, BK inhibited the M-type K super(+) current I sub(K(M)). St...

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Veröffentlicht in:	Neuron (Cambridge, Mass.) Mass.), 1995-01, Vol.14 (2), p.399-405
Hauptverfasser:	Jones, S, Brown, DA, Milligan, G, Willer, E, Buckley, N J, Caulfield, M P
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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