Low-level laser therapy promotes proliferation and invasion of oral squamous cell carcinoma cells
Low-level laser therapy (LLLT) has been shown to be effective in promoting cell proliferation. There is speculation that the biostimulatory effect of LLLT causes undesirable enhancement of tumor growth in neoplastic diseases since malignant cells are more susceptible to proliferative stimuli. This s...
Gespeichert in:
| Veröffentlicht in: | Lasers in medical science 2014-07, Vol.29 (4), p.1385-1395 |
|---|---|
| Hauptverfasser: | , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 1395 |
|---|---|
| container_issue | 4 |
| container_start_page | 1385 |
| container_title | Lasers in medical science |
| container_volume | 29 |
| creator | Gomes Henriques, Águida Cristina Ginani, Fernanda Oliveira, Ruth Medeiros Keesen, Tatjana Souza Lima Galvão Barboza, Carlos Augusto Oliveira Rocha, Hugo Alexandre de Castro, Jurema Freire Lisboa Della Coletta, Ricardo de Almeida Freitas, Roseana |
| description | Low-level laser therapy (LLLT) has been shown to be effective in promoting cell proliferation. There is speculation that the biostimulatory effect of LLLT causes undesirable enhancement of tumor growth in neoplastic diseases since malignant cells are more susceptible to proliferative stimuli. This study evaluated the effects of LLLT on proliferation, invasion, and expression of cyclin D1, E-cadherin, β-catenin, and MMP-9 in a tongue squamous carcinoma cell line (SCC25). Cells were irradiated with a diode laser (660 nm) using two energy densities (0.5 and 1.0 J/cm
2
). The proliferative potential was assessed by cell growth curves and cell cycle analysis, whereas the invasion of cells was evaluated using a Matrigel cell invasion assay. Expression of cyclin D1, E-cadherin, β-catenin, and MMP-9 was analyzed by immunofluorescence and flow cytometry and associated with the biological activities studied. LLLT induced significantly the proliferation of SCC25 cells at 1.0 J/cm
2
, which was accomplished by an increase in the expression of cyclin D1 and nuclear β-catenin. At 1.0 J/cm
2
, LLLT significantly reduced E-cadherin and induced MMP-9 expression, promoting SCC25 invasion. The results of this study demonstrated that LLLT exerts a stimulatory effect on proliferation and invasion of SCC25 cells, which was associated with alterations on expression of proteins studied. |
| doi_str_mv | 10.1007/s10103-014-1535-2 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1671614273</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1542003890</sourcerecordid><originalsourceid>FETCH-LOGICAL-c574t-1f28898c483f9de33a41d9182a4834b1c2c8b8fd99b25eb53b9e6084bc347a323</originalsourceid><addsrcrecordid>eNqNkc1O3TAQha0KBBfaB-gGWWLDJmXGf3GWFYIW6UrdgMTOchyHBiXxxU5AvH0dLlQICbUrz4w_H5_RIeQrwjcEKE8TAgIvAEWBksuCfSIrFLlQIG52yAqY0oWuGO6Tg5TuALBUyPfIPhOSKc7Uith1eCx6_-B72tvkI51--2g3T3QTwxAmn5ai79o8nLowUjs2tBsfbFqa0NIQbU_T_WyHMCfqfN9TZ6PrxjDY5zZ9Jrut7ZP_8nIekuuL86uzn8X614_Ls-_rwslSTAW2TOtKO6F5WzWecyuwqVAzmyeiRsecrnXbVFXNpK8lryuvQIvacVFazvghOdnqZsP3s0-TGbq0OLCjz94MqhIVClbyf6NSSsDsR_0HKhgA1xVk9PgdehfmOOadFwqRI4eFwi3lYkgp-tZsYjfY-GQQzJKq2aZqcqpmSdUsqx29KM_14Ju_L15jzADbAilfjbc-vvn6Q9U_9HurlQ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1541131300</pqid></control><display><type>article</type><title>Low-level laser therapy promotes proliferation and invasion of oral squamous cell carcinoma cells</title><source>MEDLINE</source><source>SpringerLink Journals - AutoHoldings</source><creator>Gomes Henriques, Águida Cristina ; Ginani, Fernanda ; Oliveira, Ruth Medeiros ; Keesen, Tatjana Souza Lima ; Galvão Barboza, Carlos Augusto ; Oliveira Rocha, Hugo Alexandre ; de Castro, Jurema Freire Lisboa ; Della Coletta, Ricardo ; de Almeida Freitas, Roseana</creator><creatorcontrib>Gomes Henriques, Águida Cristina ; Ginani, Fernanda ; Oliveira, Ruth Medeiros ; Keesen, Tatjana Souza Lima ; Galvão Barboza, Carlos Augusto ; Oliveira Rocha, Hugo Alexandre ; de Castro, Jurema Freire Lisboa ; Della Coletta, Ricardo ; de Almeida Freitas, Roseana</creatorcontrib><description>Low-level laser therapy (LLLT) has been shown to be effective in promoting cell proliferation. There is speculation that the biostimulatory effect of LLLT causes undesirable enhancement of tumor growth in neoplastic diseases since malignant cells are more susceptible to proliferative stimuli. This study evaluated the effects of LLLT on proliferation, invasion, and expression of cyclin D1, E-cadherin, β-catenin, and MMP-9 in a tongue squamous carcinoma cell line (SCC25). Cells were irradiated with a diode laser (660 nm) using two energy densities (0.5 and 1.0 J/cm
2
). The proliferative potential was assessed by cell growth curves and cell cycle analysis, whereas the invasion of cells was evaluated using a Matrigel cell invasion assay. Expression of cyclin D1, E-cadherin, β-catenin, and MMP-9 was analyzed by immunofluorescence and flow cytometry and associated with the biological activities studied. LLLT induced significantly the proliferation of SCC25 cells at 1.0 J/cm
2
, which was accomplished by an increase in the expression of cyclin D1 and nuclear β-catenin. At 1.0 J/cm
2
, LLLT significantly reduced E-cadherin and induced MMP-9 expression, promoting SCC25 invasion. The results of this study demonstrated that LLLT exerts a stimulatory effect on proliferation and invasion of SCC25 cells, which was associated with alterations on expression of proteins studied.</description><identifier>ISSN: 0268-8921</identifier><identifier>EISSN: 1435-604X</identifier><identifier>DOI: 10.1007/s10103-014-1535-2</identifier><identifier>PMID: 24526326</identifier><identifier>CODEN: LMSCEZ</identifier><language>eng</language><publisher>London: Springer London</publisher><subject>Alterations ; beta Catenin - metabolism ; Biotechnology ; Cadherins - metabolism ; Carcinoma, Squamous Cell - metabolism ; Carcinoma, Squamous Cell - pathology ; Carcinoma, Squamous Cell - radiotherapy ; Cell Cycle - radiation effects ; Cell Line, Tumor ; Cell Proliferation - radiation effects ; Cells ; Cyclin D1 - metabolism ; Dentistry ; Flow cytometry ; Humans ; Immunofluorescence ; Laser surgery ; Lasers ; Low-Level Light Therapy ; Matrix Metalloproteinase 9 - metabolism ; Medicine ; Medicine & Public Health ; Mouth Neoplasms - metabolism ; Mouth Neoplasms - pathology ; Mouth Neoplasms - radiotherapy ; Neoplasm Invasiveness ; Optical Devices ; Optics ; Oral cancer ; Original Article ; Photonics ; Proteins ; Quantum Optics ; Stimuli ; Therapy</subject><ispartof>Lasers in medical science, 2014-07, Vol.29 (4), p.1385-1395</ispartof><rights>Springer-Verlag London 2014</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c574t-1f28898c483f9de33a41d9182a4834b1c2c8b8fd99b25eb53b9e6084bc347a323</citedby><cites>FETCH-LOGICAL-c574t-1f28898c483f9de33a41d9182a4834b1c2c8b8fd99b25eb53b9e6084bc347a323</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s10103-014-1535-2$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s10103-014-1535-2$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27903,27904,41467,42536,51297</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24526326$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Gomes Henriques, Águida Cristina</creatorcontrib><creatorcontrib>Ginani, Fernanda</creatorcontrib><creatorcontrib>Oliveira, Ruth Medeiros</creatorcontrib><creatorcontrib>Keesen, Tatjana Souza Lima</creatorcontrib><creatorcontrib>Galvão Barboza, Carlos Augusto</creatorcontrib><creatorcontrib>Oliveira Rocha, Hugo Alexandre</creatorcontrib><creatorcontrib>de Castro, Jurema Freire Lisboa</creatorcontrib><creatorcontrib>Della Coletta, Ricardo</creatorcontrib><creatorcontrib>de Almeida Freitas, Roseana</creatorcontrib><title>Low-level laser therapy promotes proliferation and invasion of oral squamous cell carcinoma cells</title><title>Lasers in medical science</title><addtitle>Lasers Med Sci</addtitle><addtitle>Lasers Med Sci</addtitle><description>Low-level laser therapy (LLLT) has been shown to be effective in promoting cell proliferation. There is speculation that the biostimulatory effect of LLLT causes undesirable enhancement of tumor growth in neoplastic diseases since malignant cells are more susceptible to proliferative stimuli. This study evaluated the effects of LLLT on proliferation, invasion, and expression of cyclin D1, E-cadherin, β-catenin, and MMP-9 in a tongue squamous carcinoma cell line (SCC25). Cells were irradiated with a diode laser (660 nm) using two energy densities (0.5 and 1.0 J/cm
2
). The proliferative potential was assessed by cell growth curves and cell cycle analysis, whereas the invasion of cells was evaluated using a Matrigel cell invasion assay. Expression of cyclin D1, E-cadherin, β-catenin, and MMP-9 was analyzed by immunofluorescence and flow cytometry and associated with the biological activities studied. LLLT induced significantly the proliferation of SCC25 cells at 1.0 J/cm
2
, which was accomplished by an increase in the expression of cyclin D1 and nuclear β-catenin. At 1.0 J/cm
2
, LLLT significantly reduced E-cadherin and induced MMP-9 expression, promoting SCC25 invasion. The results of this study demonstrated that LLLT exerts a stimulatory effect on proliferation and invasion of SCC25 cells, which was associated with alterations on expression of proteins studied.</description><subject>Alterations</subject><subject>beta Catenin - metabolism</subject><subject>Biotechnology</subject><subject>Cadherins - metabolism</subject><subject>Carcinoma, Squamous Cell - metabolism</subject><subject>Carcinoma, Squamous Cell - pathology</subject><subject>Carcinoma, Squamous Cell - radiotherapy</subject><subject>Cell Cycle - radiation effects</subject><subject>Cell Line, Tumor</subject><subject>Cell Proliferation - radiation effects</subject><subject>Cells</subject><subject>Cyclin D1 - metabolism</subject><subject>Dentistry</subject><subject>Flow cytometry</subject><subject>Humans</subject><subject>Immunofluorescence</subject><subject>Laser surgery</subject><subject>Lasers</subject><subject>Low-Level Light Therapy</subject><subject>Matrix Metalloproteinase 9 - metabolism</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Mouth Neoplasms - metabolism</subject><subject>Mouth Neoplasms - pathology</subject><subject>Mouth Neoplasms - radiotherapy</subject><subject>Neoplasm Invasiveness</subject><subject>Optical Devices</subject><subject>Optics</subject><subject>Oral cancer</subject><subject>Original Article</subject><subject>Photonics</subject><subject>Proteins</subject><subject>Quantum Optics</subject><subject>Stimuli</subject><subject>Therapy</subject><issn>0268-8921</issn><issn>1435-604X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNqNkc1O3TAQha0KBBfaB-gGWWLDJmXGf3GWFYIW6UrdgMTOchyHBiXxxU5AvH0dLlQICbUrz4w_H5_RIeQrwjcEKE8TAgIvAEWBksuCfSIrFLlQIG52yAqY0oWuGO6Tg5TuALBUyPfIPhOSKc7Uith1eCx6_-B72tvkI51--2g3T3QTwxAmn5ai79o8nLowUjs2tBsfbFqa0NIQbU_T_WyHMCfqfN9TZ6PrxjDY5zZ9Jrut7ZP_8nIekuuL86uzn8X614_Ls-_rwslSTAW2TOtKO6F5WzWecyuwqVAzmyeiRsecrnXbVFXNpK8lryuvQIvacVFazvghOdnqZsP3s0-TGbq0OLCjz94MqhIVClbyf6NSSsDsR_0HKhgA1xVk9PgdehfmOOadFwqRI4eFwi3lYkgp-tZsYjfY-GQQzJKq2aZqcqpmSdUsqx29KM_14Ju_L15jzADbAilfjbc-vvn6Q9U_9HurlQ</recordid><startdate>20140701</startdate><enddate>20140701</enddate><creator>Gomes Henriques, Águida Cristina</creator><creator>Ginani, Fernanda</creator><creator>Oliveira, Ruth Medeiros</creator><creator>Keesen, Tatjana Souza Lima</creator><creator>Galvão Barboza, Carlos Augusto</creator><creator>Oliveira Rocha, Hugo Alexandre</creator><creator>de Castro, Jurema Freire Lisboa</creator><creator>Della Coletta, Ricardo</creator><creator>de Almeida Freitas, Roseana</creator><general>Springer London</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QO</scope><scope>7RV</scope><scope>7SP</scope><scope>7U5</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H8D</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB0</scope><scope>L7M</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M7P</scope><scope>NAPCQ</scope><scope>P5Z</scope><scope>P62</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>20140701</creationdate><title>Low-level laser therapy promotes proliferation and invasion of oral squamous cell carcinoma cells</title><author>Gomes Henriques, Águida Cristina ; Ginani, Fernanda ; Oliveira, Ruth Medeiros ; Keesen, Tatjana Souza Lima ; Galvão Barboza, Carlos Augusto ; Oliveira Rocha, Hugo Alexandre ; de Castro, Jurema Freire Lisboa ; Della Coletta, Ricardo ; de Almeida Freitas, Roseana</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c574t-1f28898c483f9de33a41d9182a4834b1c2c8b8fd99b25eb53b9e6084bc347a323</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Alterations</topic><topic>beta Catenin - metabolism</topic><topic>Biotechnology</topic><topic>Cadherins - metabolism</topic><topic>Carcinoma, Squamous Cell - metabolism</topic><topic>Carcinoma, Squamous Cell - pathology</topic><topic>Carcinoma, Squamous Cell - radiotherapy</topic><topic>Cell Cycle - radiation effects</topic><topic>Cell Line, Tumor</topic><topic>Cell Proliferation - radiation effects</topic><topic>Cells</topic><topic>Cyclin D1 - metabolism</topic><topic>Dentistry</topic><topic>Flow cytometry</topic><topic>Humans</topic><topic>Immunofluorescence</topic><topic>Laser surgery</topic><topic>Lasers</topic><topic>Low-Level Light Therapy</topic><topic>Matrix Metalloproteinase 9 - metabolism</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Mouth Neoplasms - metabolism</topic><topic>Mouth Neoplasms - pathology</topic><topic>Mouth Neoplasms - radiotherapy</topic><topic>Neoplasm Invasiveness</topic><topic>Optical Devices</topic><topic>Optics</topic><topic>Oral cancer</topic><topic>Original Article</topic><topic>Photonics</topic><topic>Proteins</topic><topic>Quantum Optics</topic><topic>Stimuli</topic><topic>Therapy</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Gomes Henriques, Águida Cristina</creatorcontrib><creatorcontrib>Ginani, Fernanda</creatorcontrib><creatorcontrib>Oliveira, Ruth Medeiros</creatorcontrib><creatorcontrib>Keesen, Tatjana Souza Lima</creatorcontrib><creatorcontrib>Galvão Barboza, Carlos Augusto</creatorcontrib><creatorcontrib>Oliveira Rocha, Hugo Alexandre</creatorcontrib><creatorcontrib>de Castro, Jurema Freire Lisboa</creatorcontrib><creatorcontrib>Della Coletta, Ricardo</creatorcontrib><creatorcontrib>de Almeida Freitas, Roseana</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Biotechnology Research Abstracts</collection><collection>Nursing & Allied Health Database</collection><collection>Electronics & Communications Abstracts</collection><collection>Solid State and Superconductivity Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>Advanced Technologies & Aerospace Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Technology Collection</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Aerospace Database</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Advanced Technologies Database with Aerospace</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Biological Science Database</collection><collection>Nursing & Allied Health Premium</collection><collection>Advanced Technologies & Aerospace Database</collection><collection>ProQuest Advanced Technologies & Aerospace Collection</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>Lasers in medical science</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Gomes Henriques, Águida Cristina</au><au>Ginani, Fernanda</au><au>Oliveira, Ruth Medeiros</au><au>Keesen, Tatjana Souza Lima</au><au>Galvão Barboza, Carlos Augusto</au><au>Oliveira Rocha, Hugo Alexandre</au><au>de Castro, Jurema Freire Lisboa</au><au>Della Coletta, Ricardo</au><au>de Almeida Freitas, Roseana</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Low-level laser therapy promotes proliferation and invasion of oral squamous cell carcinoma cells</atitle><jtitle>Lasers in medical science</jtitle><stitle>Lasers Med Sci</stitle><addtitle>Lasers Med Sci</addtitle><date>2014-07-01</date><risdate>2014</risdate><volume>29</volume><issue>4</issue><spage>1385</spage><epage>1395</epage><pages>1385-1395</pages><issn>0268-8921</issn><eissn>1435-604X</eissn><coden>LMSCEZ</coden><abstract>Low-level laser therapy (LLLT) has been shown to be effective in promoting cell proliferation. There is speculation that the biostimulatory effect of LLLT causes undesirable enhancement of tumor growth in neoplastic diseases since malignant cells are more susceptible to proliferative stimuli. This study evaluated the effects of LLLT on proliferation, invasion, and expression of cyclin D1, E-cadherin, β-catenin, and MMP-9 in a tongue squamous carcinoma cell line (SCC25). Cells were irradiated with a diode laser (660 nm) using two energy densities (0.5 and 1.0 J/cm
2
). The proliferative potential was assessed by cell growth curves and cell cycle analysis, whereas the invasion of cells was evaluated using a Matrigel cell invasion assay. Expression of cyclin D1, E-cadherin, β-catenin, and MMP-9 was analyzed by immunofluorescence and flow cytometry and associated with the biological activities studied. LLLT induced significantly the proliferation of SCC25 cells at 1.0 J/cm
2
, which was accomplished by an increase in the expression of cyclin D1 and nuclear β-catenin. At 1.0 J/cm
2
, LLLT significantly reduced E-cadherin and induced MMP-9 expression, promoting SCC25 invasion. The results of this study demonstrated that LLLT exerts a stimulatory effect on proliferation and invasion of SCC25 cells, which was associated with alterations on expression of proteins studied.</abstract><cop>London</cop><pub>Springer London</pub><pmid>24526326</pmid><doi>10.1007/s10103-014-1535-2</doi><tpages>11</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0268-8921 |
| ispartof | Lasers in medical science, 2014-07, Vol.29 (4), p.1385-1395 |
| issn | 0268-8921 1435-604X |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1671614273 |
| source | MEDLINE; SpringerLink Journals - AutoHoldings |
| subjects | Alterations beta Catenin - metabolism Biotechnology Cadherins - metabolism Carcinoma, Squamous Cell - metabolism Carcinoma, Squamous Cell - pathology Carcinoma, Squamous Cell - radiotherapy Cell Cycle - radiation effects Cell Line, Tumor Cell Proliferation - radiation effects Cells Cyclin D1 - metabolism Dentistry Flow cytometry Humans Immunofluorescence Laser surgery Lasers Low-Level Light Therapy Matrix Metalloproteinase 9 - metabolism Medicine Medicine & Public Health Mouth Neoplasms - metabolism Mouth Neoplasms - pathology Mouth Neoplasms - radiotherapy Neoplasm Invasiveness Optical Devices Optics Oral cancer Original Article Photonics Proteins Quantum Optics Stimuli Therapy |
| title | Low-level laser therapy promotes proliferation and invasion of oral squamous cell carcinoma cells |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-27T19%3A10%3A26IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Low-level%20laser%20therapy%20promotes%20proliferation%20and%20invasion%20of%20oral%20squamous%20cell%20carcinoma%20cells&rft.jtitle=Lasers%20in%20medical%20science&rft.au=Gomes%20Henriques,%20%C3%81guida%20Cristina&rft.date=2014-07-01&rft.volume=29&rft.issue=4&rft.spage=1385&rft.epage=1395&rft.pages=1385-1395&rft.issn=0268-8921&rft.eissn=1435-604X&rft.coden=LMSCEZ&rft_id=info:doi/10.1007/s10103-014-1535-2&rft_dat=%3Cproquest_cross%3E1542003890%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1541131300&rft_id=info:pmid/24526326&rfr_iscdi=true |