Rhodium-Catalyzed Direct Addition of Indoles to N-Sulfonylaldimines

The rhodium‐catalyzed addition of indole CH bonds to a range of aryl‐ and alkyl‐N‐sulfonylaldimines is reported. The reaction proceeds with high functional group compatibility and provides easy and rapid access to a wide variety of 2‐indolylmethanamine derivatives under mild reaction conditions....

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Veröffentlicht in:Advanced synthesis & catalysis 2013-02, Vol.355 (2-3), p.360-364
Hauptverfasser: Zhou, Bing, Yang, Yaxi, Lin, Sui, Li, Yuanchao
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creator Zhou, Bing
Yang, Yaxi
Lin, Sui
Li, Yuanchao
description The rhodium‐catalyzed addition of indole CH bonds to a range of aryl‐ and alkyl‐N‐sulfonylaldimines is reported. The reaction proceeds with high functional group compatibility and provides easy and rapid access to a wide variety of 2‐indolylmethanamine derivatives under mild reaction conditions.
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subjects addition reactions
Catalysis
CH activation
Derivatives
Functional groups
imines
Indoles
rhodium
Synthesis
title Rhodium-Catalyzed Direct Addition of Indoles to N-Sulfonylaldimines
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