Overproduction of fatty acids in engineered Saccharomyces cerevisiae

ABSTRACT The long hydrocarbon fatty acyl chain is energy rich, making it an ideal precursor for liquid transportation fuels and high‐value oleo chemicals. As Saccharomyces cerevisiae has many advantages for industrial production compared to Escherichia coli. Here, we attempted to engineer Saccharomy...

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Veröffentlicht in:	Biotechnology and bioengineering 2014-09, Vol.111 (9), p.1841-1852
Hauptverfasser:	Li, Xiaowei, Guo, Daoyi, Cheng, Yongbo, Zhu, Fayin, Deng, Zixin, Liu, Tiangang
Format:	Artikel
Sprache:	eng
Schlagworte:	acetyl-CoA carboxylase Bioengineering Biofuels Biosynthesis cell-free Escherichia coli Ethyl alcohol Fatty acids Fatty Acids - metabolism fatty acids biosynthesis fatty acids derived biofuel Gene Deletion Gene Expression Metabolic Engineering Metabolic Flux Analysis Metabolic Networks and Pathways - genetics Phosphorylation Precursors Saccharomyces cerevisiae Saccharomyces cerevisiae - genetics Saccharomyces cerevisiae - metabolism Strain Synthesis Yeast
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