Ultrasensitive electrochemical immunosensor for CA 15-3 using thionine-nanoporous gold―graphene as a platform and horseradish peroxidase-encapsulated liposomes as signal amplification

This paper describes a novel electrochemical immunosensor using a nanoporous gold (NPG)/graphene (GN) hybrid platform combined with horseradish peroxidase (HRP)-encapsulated liposomes as labels for the sensitive detection of cancer antigen 15-3 (CA 15-3). The electrochemical detection was based on t...

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Veröffentlicht in:	Analyst (London) 2012-10, Vol.137 (19), p.4440-4447
Hauptverfasser:	Ge, Shenguang, Jiao, Xiuling, Chen, Dairong
Format:	Artikel
Sprache:	eng
Schlagworte:	Analytical chemistry Antigens Assaying Chemistry Electrochemical methods Electrochemical Techniques Exact sciences and technology General, instrumentation Gold - chemistry Graphene Graphite - chemistry Horseradish Peroxidase - chemistry Horseradish Peroxidase - metabolism Humans Hydrogen Peroxide - chemistry Immunoassay Immunosensors Liposomes Liposomes - chemistry Miscellaneous Mucin-1 - blood Nanopores - ultrastructure Nanostructure Oxidation-Reduction Phenothiazines - chemistry Platforms
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