Quantitation of ribavirin in human plasma and red blood cells using LC–MS/MS

LC–MS/MS has been applied for the rapid determination of the nucleoside analogue ribavirin in human plasma and red blood cells. The incorporation of ribavirin to the erythrocytes has been assayed after in vitro incubation of the cells at different concentrations of the antiviral drug. After protein...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of separation science 2014-03, Vol.37 (5), p.476-483
Hauptverfasser:	Ferreirós, N, Labocha, S, El‐Duweik, J, Schlecker, C, Lötsch, J, Geisslinger, G
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Assaying Biological and medical sciences Blood Calibration Chromatography Chromatography, High Pressure Liquid - methods Drugs Erythrocytes Erythrocytes - chemistry General pharmacology Human Humans Liquid chromatography Mass spectrometry Medical sciences Monitoring patients Pharmacology Pharmacology. Drug treatments Plasma Plasma - chemistry Precipitation Red blood cells Ribavirin Ribavirin - blood Separation storage time Tandem mass spectrometry Tandem Mass Spectrometry - methods uridine Validation
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!