Antinociceptive effect of Butea monosperma on vincristine-induced neuropathic pain model in rats

Neuropathic pain is a chronic neurodegenerative disease. It is well characterized by spontaneous pain, hyperalgesia, hypothesia, dysesthesia and allodynia. The present study was designed to investigate the antinociceptive potential of Butea monosperma on vincristine-induced painful neuropathy in rat...

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Veröffentlicht in:	Toxicology and industrial health 2013-02, Vol.29 (1), p.3-13
Hauptverfasser:	Thiagarajan, Venkata Rathina Kumar, Shanmugam, Palanichamy, Krishnan, Uma Maheswari, Muthuraman, Arunachalam, Singh, Nirmal
Format:	Artikel
Sprache:	eng
Schlagworte:	Analgesics Analgesics - pharmacology Animals Antineoplastic Agents, Phytogenic - toxicity Antioxidants - pharmacology Behavior, Animal - drug effects Behavioural Biochemistry Butea - chemistry Calcium Calcium - metabolism Channels Chemotherapy Disease Models, Animal Drug dosages Female gamma-Aminobutyric Acid - analogs & derivatives gamma-Aminobutyric Acid - pharmacology Glutathione - metabolism Herbal medicine Hindlimb Hot Temperature Hyperalgesia Hyperalgesia - drug therapy Hyperalgesia - physiopathology Leaves Male Nerves Neuralgia - chemically induced Neuralgia - drug therapy Neuralgia - metabolism Neuralgia - pathology Oxidative Stress - drug effects Pain Pain Measurement Peripheral Nervous System Diseases - chemically induced Peripheral Nervous System Diseases - drug therapy Peripheral Nervous System Diseases - metabolism Peripheral Nervous System Diseases - pathology Pharmaceutical sciences Pharmacy Plant Extracts - pharmacology Plant Leaves - chemistry Pregabalin Rats Rats, Wistar Sciatic Nerve - drug effects Sciatic Nerve - metabolism Sciatic Nerve - pathology Tail Thiobarbituric Acid Reactive Substances - metabolism Toxicology Treatment Outcome Vincristine - toxicity
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